1n7k: Difference between revisions

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{{Seed}}
[[Image:1n7k.png|left|200px]]


<!--
==Unique tetrameric structure of deoxyribose phosphate aldolase from Aeropyrum pernix==
The line below this paragraph, containing "STRUCTURE_1n7k", creates the "Structure Box" on the page.
<StructureSection load='1n7k' size='340' side='right'caption='[[1n7k]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1n7k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N7K FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n7k OCA], [https://pdbe.org/1n7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n7k RCSB], [https://www.ebi.ac.uk/pdbsum/1n7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n7k ProSAT], [https://www.topsan.org/Proteins/RSGI/1n7k TOPSAN]</span></td></tr>
{{STRUCTURE_1n7k| PDB=1n7k |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/DEOC_AERPE DEOC_AERPE] Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.<ref>PMID:12529358</ref>  
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n7/1n7k_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n7k ConSurf].
<div style="clear:both"></div>


===Unique tetrameric structure of deoxyribose phosphate aldolase from Aeropyrum pernix===
==See Also==
 
*[[Aldolase 3D structures|Aldolase 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_12529358}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 12529358 is the PubMed ID number.
</StructureSection>
-->
{{ABSTRACT_PUBMED_12529358}}
 
==About this Structure==
1N7K is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7K OCA].
 
==Reference==
The first crystal structure of archaeal aldolase. Unique tetrameric structure of 2-deoxy-d-ribose-5-phosphate aldolase from the hyperthermophilic archaea Aeropyrum pernix., Sakuraba H, Tsuge H, Shimoya I, Kawakami R, Goda S, Kawarabayasi Y, Katunuma N, Ago H, Miyano M, Ohshima T, J Biol Chem. 2003 Mar 21;278(12):10799-806. Epub 2003 Jan 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12529358 12529358]
[[Category: Aeropyrum pernix]]
[[Category: Aeropyrum pernix]]
[[Category: Deoxyribose-phosphate aldolase]]
[[Category: Large Structures]]
[[Category: Ago, H.]]
[[Category: Ago H]]
[[Category: Katunuma, N.]]
[[Category: Katunuma N]]
[[Category: Miyano, M.]]
[[Category: Miyano M]]
[[Category: Ohshima, T.]]
[[Category: Ohshima T]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Sakuraba H]]
[[Category: Sakuraba, H.]]
[[Category: Shimoya I]]
[[Category: Shimoya, I.]]
[[Category: Tsuge H]]
[[Category: Tsuge, H.]]
[[Category: A pernix]]
[[Category: Aldolase]]
[[Category: Alpha-beta tim barrel]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Tetramer]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 09:59:12 2008''

Latest revision as of 13:27, 13 March 2024

Unique tetrameric structure of deoxyribose phosphate aldolase from Aeropyrum pernix

1n7k, resolution 2.00Å

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