1k4z: Difference between revisions

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{{Seed}}
[[Image:1k4z.png|left|200px]]


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==C-terminal Domain of Cyclase Associated Protein==
The line below this paragraph, containing "STRUCTURE_1k4z", creates the "Structure Box" on the page.
<StructureSection load='1k4z' size='340' side='right'caption='[[1k4z]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1k4z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1f5i 1f5i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K4Z FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k4z OCA], [https://pdbe.org/1k4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k4z RCSB], [https://www.ebi.ac.uk/pdbsum/1k4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k4z ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1k4z TOPSAN]</span></td></tr>
{{STRUCTURE_1k4z| PDB=1k4z |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAP_YEAST CAP_YEAST] The N-terminal domain binds to adenylyl cyclase, thereby enabling adenylyl cyclase to be activated by upstream regulatory signals, such as Ras. The C-terminal domain is required for normal cellular morphology and growth control.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/1k4z_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k4z ConSurf].
<div style="clear:both"></div>


===C-terminal Domain of Cyclase Associated Protein===
==See Also==
 
*[[3D Adenylyl cyclase 3D structures|3D Adenylyl cyclase 3D structures]]
 
__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_15311924}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 15311924 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15311924}}
 
==About this Structure==
1K4Z is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1f5i 1f5i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K4Z OCA].
 
==Reference==
Crystal structure of the actin binding domain of the cyclase-associated protein., Dodatko T, Fedorov AA, Grynberg M, Patskovsky Y, Rozwarski DA, Jaroszewski L, Aronoff-Spencer E, Kondraskina E, Irving T, Godzik A, Almo SC, Biochemistry. 2004 Aug 24;43(33):10628-41. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15311924 15311924]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Almo, S C.]]
[[Category: Almo SC]]
[[Category: Burley, S K.]]
[[Category: Burley SK]]
[[Category: Dodatko, T.]]
[[Category: Dodatko T]]
[[Category: Fedorov, A A.]]
[[Category: Fedorov AA]]
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: Rozwarski DA]]
[[Category: Rozwarski, D A.]]
[[Category: Actin-binding]]
[[Category: Intertwined dimer]]
[[Category: New york structural genomix research consortium]]
[[Category: Nysgxrc]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Right-handed parallel beta-helix]]
[[Category: Structural genomic]]
 
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Retrieved from "https://proteopedia.org/1k4z"