2rn4: Difference between revisions

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{{Seed}}
[[Image:2rn4.jpg|left|200px]]


<!--
==Solution structure of the alkaline proteinase inhibitor APRin from Pseudomonas aeruginosa==
The line below this paragraph, containing "STRUCTURE_2rn4", creates the "Structure Box" on the page.
<StructureSection load='2rn4' size='340' side='right'caption='[[2rn4]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2rn4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RN4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RN4 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rn4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rn4 OCA], [https://pdbe.org/2rn4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rn4 RCSB], [https://www.ebi.ac.uk/pdbsum/2rn4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rn4 ProSAT]</span></td></tr>
{{STRUCTURE_2rn4|  PDB=2rn4  |  SCENE=  }}
</table>
 
== Function ==
===Solution structure of the alkaline proteinase inhibitor APRin from Pseudomonas aeruginosa===
[https://www.uniprot.org/uniprot/INH_PSEAE INH_PSEAE] Inhibitor of the alkaline protease. It forms a non-covalent bond with the protease and may prevent its autocatalytic cleavage in the periplasm (By similarity).
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
2RN4 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RN4 OCA].  
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rn/2rn4_consurf.spt"</scriptWhenChecked>
==Reference==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
NMR structure note: alkaline proteinase inhibitor APRin from Pseudomonas aeruginosa., Arumugam S, Gray RD, Lane AN, J Biomol NMR. 2008 Mar;40(3):213-7. Epub 2008 Jan 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18214691 18214691]
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
1H, 15N and 13C assignments of the alkaline proteinase inhibitor APRin from Pseudomonas aeruginosa., Arumugam S, Gray RD, Lane AN, J Biomol NMR. 2005 Mar;31(3):265-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15803404 15803404]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rn4 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Arumugam, S.]]
[[Category: Arumugam S]]
[[Category: Gray, R D.]]
[[Category: Gray RD]]
[[Category: Lane, A N.]]
[[Category: Lane AN]]
[[Category: Hydrolase inhibitor]]
[[Category: Metalloenzyme inhibitor]]
[[Category: Metalloprotease inhibitor]]
[[Category: Periplasm]]
[[Category: Protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 20 07:37:16 2008''

Latest revision as of 01:24, 21 November 2024

Solution structure of the alkaline proteinase inhibitor APRin from Pseudomonas aeruginosa

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