3bcu: Difference between revisions

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{{Seed}}
[[Image:3bcu.jpg|left|200px]]


<!--
==Glucogen Phosphorylase complex with thymidine==
The line below this paragraph, containing "STRUCTURE_3bcu", creates the "Structure Box" on the page.
<StructureSection load='3bcu' size='340' side='right'caption='[[3bcu]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3bcu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BCU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BCU FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=THM:THYMIDINE'>THM</scene></td></tr>
{{STRUCTURE_3bcu| PDB=3bcu |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bcu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bcu OCA], [https://pdbe.org/3bcu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bcu RCSB], [https://www.ebi.ac.uk/pdbsum/3bcu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bcu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PYGM_RABIT PYGM_RABIT] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bc/3bcu_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bcu ConSurf].
<div style="clear:both"></div>


===Glucogen Phosphorylase complex with thymidine===
==See Also==
 
*[[Glycogen phosphorylase 3D structures|Glycogen phosphorylase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3BCU is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BCU OCA].
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Phosphorylase]]
[[Category: Chrysina ED]]
[[Category: Chrysina, E D.]]
[[Category: Hadjiloi T]]
[[Category: Hadjiloi, T.]]
[[Category: Hayes JM]]
[[Category: Hayes, J M.]]
[[Category: Oikonomakos NG]]
[[Category: Oikonomakos, N G.]]
[[Category: Sovantzis DA]]
[[Category: Sovantzis, D A.]]
[[Category: Zographos SE]]
[[Category: Zographos, S E.]]
[[Category: Acetylation]]
[[Category: Allosteric enzyme]]
[[Category: Carbohydrate metabolism]]
[[Category: Glycogen metabolism]]
[[Category: Glycogenolysis]]
[[Category: Glycosyltransferase]]
[[Category: Nucleotide-binding]]
[[Category: Phosphorylation]]
[[Category: Pyridoxal phosphate]]
[[Category: Transferase]]
[[Category: Type 2 diabetes]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 20 07:39:23 2008''
Retrieved from "https://proteopedia.org/3bcu"