3ckj: Difference between revisions

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{{Seed}}
[[Image:3ckj.png|left|200px]]


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==Crystal Structure of a Mycobacterial Protein==
The line below this paragraph, containing "STRUCTURE_3ckj", creates the "Structure Box" on the page.
<StructureSection load='3ckj' size='340' side='right'caption='[[3ckj]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3ckj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_avium_subsp._paratuberculosis_K-10 Mycobacterium avium subsp. paratuberculosis K-10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CKJ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
{{STRUCTURE_3ckj|  PDB=3ckj  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ckj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ckj OCA], [https://pdbe.org/3ckj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ckj RCSB], [https://www.ebi.ac.uk/pdbsum/3ckj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ckj ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of a Mycobacterial Protein===
== Function ==
 
[https://www.uniprot.org/uniprot/GPGS_MYCPA GPGS_MYCPA] Involved in the biosynthesis of methylglucose lipopolysaccharides (MGLPs). Catalyzes the condensation of UDP-glucose and 3-phospho-glycerate (3-PGA) to yield glucosyl-3-phosphoglycerate (GPG). Although UDP-glucose is the natural donor sugar, GpgS can also use UDP-GalNAc, UDPGlcNAc, UDP-alpha-L-arabinose, UDP-Gal, UDP-Glc, UDP-alpha-Dglucuronic acid, and UDP-alpha-D-xylose as donor substrates.<ref>PMID:18667419</ref>
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_18667419}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 18667419 is the PubMed ID number.
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ck/3ckj_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_18667419}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
3CKJ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_avium_subsp._paratuberculosis Mycobacterium avium subsp. paratuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKJ OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ckj ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
Crystal structure of a UDP-glucose-specific glycosyltransferase from a Mycobacterium species., Fulton Z, McAlister A, Wilce MC, Brammananth R, Zaker-Tabrizi L, Perugini MA, Bottomley SP, Coppel RL, Crellin PK, Rossjohn J, Beddoe T, J Biol Chem. 2008 Oct 10;283(41):27881-90. Epub 2008 Jul 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18667419 18667419]
<references/>
[[Category: Mycobacterium avium subsp. paratuberculosis]]
__TOC__
[[Category: Marland, Z.]]
</StructureSection>
[[Category: Rossjohn, J.]]
[[Category: Large Structures]]
[[Category: Mycobacteria]]
[[Category: Mycobacterium avium subsp. paratuberculosis K-10]]
[[Category: Unknown function]]
[[Category: Marland Z]]
 
[[Category: Rossjohn J]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 20 07:54:50 2008''

Latest revision as of 09:36, 21 February 2024

Crystal Structure of a Mycobacterial Protein

3ckj, resolution 1.80Å

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