3eay: Difference between revisions

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{{Seed}}
[[Image:3eay.png|left|200px]]


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==Crystal structure of the human SENP7 catalytic domain==
The line below this paragraph, containing "STRUCTURE_3eay", creates the "Structure Box" on the page.
<StructureSection load='3eay' size='340' side='right'caption='[[3eay]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3eay]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EAY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EAY FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3eay|  PDB=3eay |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eay FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eay OCA], [https://pdbe.org/3eay PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eay RCSB], [https://www.ebi.ac.uk/pdbsum/3eay PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eay ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SENP7_HUMAN SENP7_HUMAN] Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms.<ref>PMID:18799455</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ea/3eay_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3eay ConSurf].
<div style="clear:both"></div>


===Crystal structure of the human SENP7 catalytic domain===
==See Also==
 
*[[Sentrin-specific protease|Sentrin-specific protease]]
 
== References ==
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<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_18799455}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 18799455 is the PubMed ID number.
</StructureSection>
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{{ABSTRACT_PUBMED_18799455}}
 
==About this Structure==
3EAY is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EAY OCA].
 
==Reference==
Structure of the Human SENP7 Catalytic Domain and Poly-SUMO Deconjugation Activities for SENP6 and SENP7., Lima CD, Reverter D, J Biol Chem. 2008 Nov 14;283(46):32045-55. Epub 2008 Sep 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18799455 18799455]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Lima, C D.]]
[[Category: Large Structures]]
[[Category: Reverter, D.]]
[[Category: Lima CD]]
[[Category: Alternative splicing]]
[[Category: Reverter D]]
[[Category: Crystal]]
[[Category: Hydrolase]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Senp]]
[[Category: Sentrin-specific protease]]
[[Category: Sumo]]
[[Category: Thiol protease]]
[[Category: Ubiquitin]]
[[Category: Ubl conjugation pathway]]
[[Category: Ulp]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 26 20:04:41 2008''
Retrieved from "https://proteopedia.org/3eay"