3f6m: Difference between revisions

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{{Seed}}
[[Image:3f6m.jpg|left|200px]]


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==Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF from Yersinia pestis==
The line below this paragraph, containing "STRUCTURE_3f6m", creates the "Structure Box" on the page.
<StructureSection load='3f6m' size='340' side='right'caption='[[3f6m]], [[Resolution|resolution]] 2.96&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3f6m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_CO92 Yersinia pestis CO92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F6M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F6M FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.96&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
{{STRUCTURE_3f6m| PDB=3f6m |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f6m OCA], [https://pdbe.org/3f6m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f6m RCSB], [https://www.ebi.ac.uk/pdbsum/3f6m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f6m ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ISPF_YERPE ISPF_YERPE] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f6/3f6m_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3f6m ConSurf].
<div style="clear:both"></div>


===Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF from Yersinia pestis===
==See Also==
 
*[[MECDP synthase 3D structures|MECDP synthase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3F6M is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F6M OCA].
[[Category: Large Structures]]
[[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]]
[[Category: Yersinia pestis CO92]]
[[Category: Yersinia pestis]]
[[Category: Anderson WF]]
[[Category: Anderson, W F.]]
[[Category: Joachimiak A]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Kim Y]]
[[Category: Joachimiak, A.]]
[[Category: Maltseva N]]
[[Category: Kim, Y.]]
[[Category: Stam J]]
[[Category: Maltseva, N.]]
[[Category: Stam, J.]]
[[Category: Alpha-beta structure]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Isoprene biosynthesis]]
[[Category: Lyase]]
[[Category: Metal-binding]]
[[Category: Structural genomics of infectious disease]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 27 13:44:27 2008''

Latest revision as of 09:51, 6 November 2024

Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF from Yersinia pestis

3f6m, resolution 2.96Å

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