2g3w: Difference between revisions

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[[Image:2g3w.png|left|200px]]


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==The Crystal Structure of YaeQ Protein from Xanthomonas axonopodis pv. citri==
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<StructureSection load='2g3w' size='340' side='right'caption='[[2g3w]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2g3w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthomonas_citri Xanthomonas citri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G3W FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
{{STRUCTURE_2g3w|  PDB=2g3w  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g3w OCA], [https://pdbe.org/2g3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g3w RCSB], [https://www.ebi.ac.uk/pdbsum/2g3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g3w ProSAT]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g3/2g3w_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g3w ConSurf].
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== Publication Abstract from PubMed ==
The YaeQ family of proteins are found in many Gram-negative and a few Gram-positive bacteria. We have determined the first structure of a member of the YaeQ family by X-ray crystallography. Comparisons with other structures indicate that YaeQ represents a new compact protein fold built around a variation of the PD-(D/E)XK nuclease motif found in type II endonucleases and enzymes involved in DNA replication, repair, and recombination. We show that catalytically important residues in the PD-(D/E)XK nuclease superfamily are spatially conserved in YaeQ and other highly conserved YaeQ residues may be poised to interact with nucleic acid structures.


===The Crystal Structure of YaeQ Protein from Xanthomonas axonopodis pv. citri===
Structure of Xanthomonas axonopodis pv. citri YaeQ reveals a new compact protein fold built around a variation of the PD-(D/E)XK nuclease motif.,Guzzo CR, Nagem RA, Barbosa JA, Farah CS Proteins. 2007 Nov 15;69(3):644-51. PMID:17623842<ref>PMID:17623842</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 2g3w" style="background-color:#fffaf0;"></div>
(as it appears on PubMed at http://www.pubmed.gov), where 17623842 is the PubMed ID number.
== References ==
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<references/>
{{ABSTRACT_PUBMED_17623842}}
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</StructureSection>
==About this Structure==
[[Category: Large Structures]]
2G3W is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Xanthomonas_axonopodis_pv._citri Xanthomonas axonopodis pv. citri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3W OCA].
[[Category: Xanthomonas citri]]
 
[[Category: Barbosa JARG]]
==Reference==
[[Category: Farah CS]]
Structure of Xanthomonas axonopodis pv. citri YaeQ reveals a new compact protein fold built around a variation of the PD-(D/E)XK nuclease motif., Guzzo CR, Nagem RA, Barbosa JA, Farah CS, Proteins. 2007 Nov 15;69(3):644-51. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17623842 17623842]
[[Category: Guzzo CR]]
 
[[Category: Nagem RAP]]
Expression, purification, crystallization and preliminary X-ray analysis of YaeQ (XAC2396) from Xanthomonas axonopodis pv. citri., Guzzo CR, Nagem RA, Galvao-Botton LM, Guimaraes BG, Medrano FJ, Barbosa JA, Farah CS, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 May 1;61(Pt, 5):493-5. Epub 2005 Apr 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16511077 16511077]
[[Category: Single protein]]
[[Category: Xanthomonas axonopodis pv. citri]]
[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
[[Category: Unknown function]]
[[Category: Xanthomonas axonopodis pv citri]]
[[Category: Yaeq protein]]
 
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