1v3f: Difference between revisions

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New page: left|200px<br /><applet load="1v3f" size="450" color="white" frame="true" align="right" spinBox="true" caption="1v3f" /> '''Solution structure of the DEP domain of mous...
 
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[[Image:1v3f.jpg|left|200px]]<br /><applet load="1v3f" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1v3f" />
'''Solution structure of the DEP domain of mouse pleckstrin2'''<br />


==About this Structure==
==Solution structure of the DEP domain of mouse pleckstrin2==
1V3F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1V3F OCA].  
<StructureSection load='1v3f' size='340' side='right'caption='[[1v3f]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1v3f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V3F FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3f OCA], [https://pdbe.org/1v3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v3f RCSB], [https://www.ebi.ac.uk/pdbsum/1v3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v3f ProSAT], [https://www.topsan.org/Proteins/RSGI/1v3f TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PLEK2_MOUSE PLEK2_MOUSE] May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation. Overexpression of pleckstrin 2 causes large lamellipodia and peripheral ruffle formation.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v3/1v3f_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v3f ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Hayashi F]]
[[Category: Hayashi, F.]]
[[Category: Inoue K]]
[[Category: Inoue, K.]]
[[Category: Yokoyama S]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Yokoyama, S.]]
[[Category: pleckstrin2]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: three-helix bundle]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 04:24:52 2007''
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