3e25: Difference between revisions

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{{Seed}}
[[Image:3e25.png|left|200px]]


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==Crystal structure of M. tuberculosis glucosyl-3-phosphoglycerate synthase==
The line below this paragraph, containing "STRUCTURE_3e25", creates the "Structure Box" on the page.
<StructureSection load='3e25' size='340' side='right'caption='[[3e25]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3e25]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E25 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E25 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PG:3-PHOSPHOGLYCERIC+ACID'>3PG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
{{STRUCTURE_3e25|  PDB=3e25  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e25 OCA], [https://pdbe.org/3e25 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e25 RCSB], [https://www.ebi.ac.uk/pdbsum/3e25 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e25 ProSAT]</span></td></tr>
 
</table>
===Crystal structure of M. tuberculosis glucosyl-3-phosphoglycerate synthase===
== Function ==
 
[https://www.uniprot.org/uniprot/GPGS_MYCTU GPGS_MYCTU] Involved in the biosynthesis of methylglucose lipopolysaccharides (MGLPs). Catalyzes the condensation of NDP-glucose and 3-phospho-glycerate (3-PGA) to yield glucosyl-3-phosphoglycerate (GPG).<ref>PMID:22637481</ref>
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_19015727}}, adds the Publication Abstract to the page
Check<jmol>
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  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e2/3e25_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_19015727}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
3E25 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E25 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e25 ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis., Pereira PJ, Empadinhas N, Albuquerque L, Sa-Moura B, da Costa MS, Macedo-Ribeiro S, PLoS ONE. 2008;3(11):e3748. Epub 2008 Nov 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19015727 19015727]
<references/>
 
__TOC__
Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase., Empadinhas N, Albuquerque L, Mendes V, Macedo-Ribeiro S, da Costa MS, FEMS Microbiol Lett. 2008 Mar;280(2):195-202. Epub 2008 Jan 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18221489 18221489]
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
[[Category: Costa MS]]
[[Category: 3-phosphoglycerate]]
[[Category: Empadinhas N]]
[[Category: Glucosyltransferase]]
[[Category: Macedo-Ribeiro S]]
[[Category: Gt81 udp-glucose]]
[[Category: Pereira PJB]]
[[Category: Mycobacterial]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 09:11:29 2008''

Latest revision as of 08:24, 20 March 2024

Crystal structure of M. tuberculosis glucosyl-3-phosphoglycerate synthase

3e25, resolution 2.70Å

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