1v6e: Difference between revisions

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New page: left|200px<br /><applet load="1v6e" size="450" color="white" frame="true" align="right" spinBox="true" caption="1v6e" /> '''Solution Structure of a N-terminal Ubiquitin...
 
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[[Image:1v6e.jpg|left|200px]]<br /><applet load="1v6e" size="450" color="white" frame="true" align="right" spinBox="true"
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'''Solution Structure of a N-terminal Ubiquitin-like Domain in Mouse Tubulin-specific Chaperone B'''<br />


==About this Structure==
==Solution Structure of a N-terminal Ubiquitin-like Domain in Mouse Tubulin-specific Chaperone B==
1V6E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1V6E OCA].  
<StructureSection load='1v6e' size='340' side='right'caption='[[1v6e]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1v6e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V6E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V6E FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v6e OCA], [https://pdbe.org/1v6e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v6e RCSB], [https://www.ebi.ac.uk/pdbsum/1v6e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v6e ProSAT], [https://www.topsan.org/Proteins/RSGI/1v6e TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TBCB_MOUSE TBCB_MOUSE] Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.<ref>PMID:17184771</ref> <ref>PMID:17217416</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v6/1v6e_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v6e ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Inoue M]]
[[Category: Inoue, M.]]
[[Category: Kigawa T]]
[[Category: Kigawa, T.]]
[[Category: Koshiba S]]
[[Category: Koshiba, S.]]
[[Category: Saito K]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Yokoyama S]]
[[Category: Saito, K.]]
[[Category: Zhao C]]
[[Category: Yokoyama, S.]]
[[Category: Zhao, C.]]
[[Category: cytoskeleton]]
[[Category: cytoskeleton-associated protein ckap1]]
[[Category: microtubule]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: tubulin folding cofactor b]]
[[Category: tubulin-specific chaperone b]]
[[Category: ubiquitin-like fold]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 04:28:16 2007''

Latest revision as of 23:58, 27 December 2023

Solution Structure of a N-terminal Ubiquitin-like Domain in Mouse Tubulin-specific Chaperone B

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