3fbk: Difference between revisions

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{{Seed}}
[[Image:3fbk.png|left|200px]]


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==Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A==
The line below this paragraph, containing "STRUCTURE_3fbk", creates the "Structure Box" on the page.
<StructureSection load='3fbk' size='340' side='right'caption='[[3fbk]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3fbk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FBK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FBK FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3fbk|  PDB=3fbk  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fbk OCA], [https://pdbe.org/3fbk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fbk RCSB], [https://www.ebi.ac.uk/pdbsum/3fbk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fbk ProSAT], [https://www.topsan.org/Proteins/NESGC/3fbk TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RGS3_HUMAN RGS3_HUMAN] Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.<ref>PMID:8602223</ref> <ref>PMID:9858594</ref> <ref>PMID:10749886</ref> <ref>PMID:11294858</ref>  


===Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A===
==See Also==
 
*[[Regulator of G-protein signaling 3D structures|Regulator of G-protein signaling 3D structures]]
 
== References ==
==About this Structure==
<references/>
3FBK is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FBK OCA].
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Acton, T B.]]
[[Category: Large Structures]]
[[Category: Ciccosanti, C.]]
[[Category: Acton TB]]
[[Category: Everett, J K.]]
[[Category: Ciccosanti C]]
[[Category: Foote, E L.]]
[[Category: Everett JK]]
[[Category: Forouhar, F.]]
[[Category: Foote EL]]
[[Category: Hunt, J F.]]
[[Category: Forouhar F]]
[[Category: Lew, S.]]
[[Category: Hunt JF]]
[[Category: Mao, L.]]
[[Category: Lew S]]
[[Category: Montelione, G T.]]
[[Category: Mao L]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Montelione GT]]
[[Category: Nair, R.]]
[[Category: Nair R]]
[[Category: Rost, B.]]
[[Category: Rost B]]
[[Category: Seetharaman, J.]]
[[Category: Seetharaman J]]
[[Category: Shastry, R.]]
[[Category: Shastry R]]
[[Category: Tong, L.]]
[[Category: Tong L]]
[[Category: Xiao, R.]]
[[Category: Xiao R]]
[[Category: All beta-sheet fold]]
[[Category: Alternative splicing]]
[[Category: Cell membrane]]
[[Category: Cytoplasm]]
[[Category: Membrane]]
[[Category: Nesg]]
[[Category: Northeast structural genomics consortium]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Signal transduction inhibitor]]
[[Category: Signaling protein]]
[[Category: Structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 15:30:40 2008''
Retrieved from "https://proteopedia.org/3fbk"