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New page: left|200px<br /><applet load="1vlv" size="450" color="white" frame="true" align="right" spinBox="true" caption="1vlv, resolution 2.25Å" /> '''Crystal structure of...
 
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[[Image:1vlv.gif|left|200px]]<br /><applet load="1vlv" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1vlv, resolution 2.25&Aring;" />
'''Crystal structure of Ornithine carbamoyltransferase (TM1097) from Thermotoga maritima at 2.25 A resolution'''<br />


==About this Structure==
==Crystal structure of Ornithine carbamoyltransferase (TM1097) from Thermotoga maritima at 2.25 A resolution==
1VLV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] with PO4 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Ornithine_carbamoyltransferase Ornithine carbamoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.3 2.1.3.3] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1VLV OCA].  
<StructureSection load='1vlv' size='340' side='right'caption='[[1vlv]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
[[Category: Ornithine carbamoyltransferase]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[1vlv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VLV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VLV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vlv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vlv OCA], [https://pdbe.org/1vlv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vlv RCSB], [https://www.ebi.ac.uk/pdbsum/1vlv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vlv ProSAT], [https://www.topsan.org/Proteins/JCSG/1vlv TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OTC_THEMA OTC_THEMA] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vl/1vlv_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vlv ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Ornithine carbamoyltransferase 3D structures|Ornithine carbamoyltransferase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
[[Category: JCSG, Joint.Center.for.Structural.Genomics.]]
[[Category: PO4]]
[[Category: jcsg]]
[[Category: joint center for structural genomics]]
[[Category: ornithine carbamoyltransferase]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomics]]
[[Category: tm1097]]
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 04:56:52 2007''
Retrieved from "https://proteopedia.org/1vlv"