2qqe: Difference between revisions

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{{Seed}}
[[Image:2qqe.png|left|200px]]


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==Thymidine Kinase from Thermotoga Maritima in complex with Thymidine==
The line below this paragraph, containing "STRUCTURE_2qqe", creates the "Structure Box" on the page.
<StructureSection load='2qqe' size='340' side='right'caption='[[2qqe]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2qqe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QQE FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=THM:THYMIDINE'>THM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_2qqe|  PDB=2qqe |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qqe OCA], [https://pdbe.org/2qqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qqe RCSB], [https://www.ebi.ac.uk/pdbsum/2qqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qqe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KITH_THEMA KITH_THEMA]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qq/2qqe_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qqe ConSurf].
<div style="clear:both"></div>


===Thymidine Kinase from Thermotoga Maritima in complex with Thymidine===
==See Also==
 
*[[Thymidine kinase 3D structures|Thymidine kinase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_18073106}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 18073106 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_18073106}}
 
==About this Structure==
2QQE is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QQE OCA].
 
==Reference==
Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes., Segura-Pena D, Lichter J, Trani M, Konrad M, Lavie A, Lutz S, Structure. 2007 Dec;15(12):1555-66. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18073106 18073106]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
[[Category: Thymidine kinase]]
[[Category: Konrad M]]
[[Category: Konrad, M.]]
[[Category: Lavie A]]
[[Category: Lavie, A.]]
[[Category: Lichter J]]
[[Category: Lichter, J.]]
[[Category: Lutz S]]
[[Category: Lutz, S.]]
[[Category: Segura-Pena D]]
[[Category: Segura-Pena, D.]]
[[Category: Trani M]]
[[Category: Trani, M.]]
[[Category: Atp-binding]]
[[Category: Close conformation]]
[[Category: Cytoplasm]]
[[Category: Dna synthesis]]
[[Category: Kinase]]
[[Category: Nucleotide-binding]]
[[Category: Tmtk in complex with thymidine]]
[[Category: Transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 31 09:07:00 2008''