1vr0: Difference between revisions

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New page: left|200px<br /><applet load="1vr0" size="450" color="white" frame="true" align="right" spinBox="true" caption="1vr0, resolution 2.49Å" /> '''Crystal structure of...
 
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[[Image:1vr0.gif|left|200px]]<br /><applet load="1vr0" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1vr0, resolution 2.49&Aring;" />
'''Crystal structure of putative 2-phosphosulfolactate phosphatase (15026306) from Clostridium acetobutylicum at 2.6 A resolution'''<br />


==About this Structure==
==Crystal structure of putative 2-phosphosulfolactate phosphatase (15026306) from Clostridium acetobutylicum at 2.6 A resolution==
1VR0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_acetobutylicum Clostridium acetobutylicum] with MG and 3SL as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/2-phosphosulfolactate_phosphatase 2-phosphosulfolactate phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.71 3.1.3.71] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1VR0 OCA].  
<StructureSection load='1vr0' size='340' side='right'caption='[[1vr0]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
 
== Structural highlights ==
==Reference==
<table><tr><td colspan='2'>[[1vr0]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_acetobutylicum Clostridium acetobutylicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VR0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VR0 FirstGlance]. <br>
Crystal structure of 2-phosphosulfolactate phosphatase (ComB) from Clostridium acetobutylicum at 2.6 A resolution reveals a new fold with a novel active site., DiDonato M, Krishna SS, Schwarzenbacher R, McMullan D, Agarwalla S, Brittain SM, Miller MD, Abdubek P, Ambing E, Axelrod HL, Canaves JM, Chiu HJ, Deacon AM, Duan L, Elsliger MA, Godzik A, Grzechnik SK, Hale J, Hampton E, Haugen J, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Koesema E, Kreusch A, Kuhn P, Lesley SA, Levin I, Morse AT, Nigoghossian E, Okach L, Oommachen S, Paulsen J, Quijano K, Reyes R, Rife CL, Spraggon G, Stevens RC, van den Bedem H, White A, Wolf G, Xu Q, Hodgson KO, Wooley J, Wilson IA, Proteins. 2006 Nov 15;65(3):771-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16927339 16927339]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49&#8491;</td></tr>
[[Category: 2-phosphosulfolactate phosphatase]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3SL:(2R)-3-SULFOLACTIC+ACID'>3SL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vr0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vr0 OCA], [https://pdbe.org/1vr0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vr0 RCSB], [https://www.ebi.ac.uk/pdbsum/1vr0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vr0 ProSAT], [https://www.topsan.org/Proteins/JCSG/1vr0 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/COMB_CLOAB COMB_CLOAB]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vr/1vr0_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vr0 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Clostridium acetobutylicum]]
[[Category: Clostridium acetobutylicum]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: JCSG, Joint.Center.for.Structural.Genomics.]]
[[Category: 3SL]]
[[Category: MG]]
[[Category: 15026306]]
[[Category: jcsg]]
[[Category: joint center for structural genomics]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: putative 2-phosphosulfolactate phosphatase]]
[[Category: structural genomics]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 05:04:57 2007''