3c9k: Difference between revisions

(12 intermediate revisions by the same user not shown)

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 3c9k is ~~ON HOLD until Paper Publication~~

==Model of Histone Octamer Tubular Crystals==

== Structural highlights ==

<table><tr><td colspan='2'>[[3c9k]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C9K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C9K FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 20Å</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c9k OCA], [https://pdbe.org/3c9k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c9k RCSB], [https://www.ebi.ac.uk/pdbsum/3c9k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c9k ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/H2A4_CHICK H2A4_CHICK] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

Check<jmol>

<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/3c9k_consurf.spt"</scriptWhenChecked>

<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>

<text>to colour the structure by Evolutionary Conservation</text>

</jmolCheckbox>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c9k ConSurf].

~~Authors: Frouws, T.D., Patterton, H.-G., Sewell, B.T.~~

==See Also==

*[[Histone 3D structures|Histone 3D structures]]

~~Description: Model of Histone Octamer Tubular Crystals~~

__TOC__

</SX>

~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Wed Jan 7 09~~:31:~~26 2009''~~

[[Category: Gallus gallus]]

[[Category: Large Structures]]

[[Category: Frouws TD]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 3c9k is ON HOLD  until Paper Publication
+==Model of Histone Octamer Tubular Crystals==
+<SX load='3c9k' size='340' side='right' viewer='molstar' caption='[[3c9k]], [[Resolution|resolution]] 20.00&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3c9k]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C9K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C9K FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 20&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c9k OCA], [https://pdbe.org/3c9k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c9k RCSB], [https://www.ebi.ac.uk/pdbsum/3c9k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c9k ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/H2A4_CHICK H2A4_CHICK] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/3c9k_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c9k ConSurf].
+<div style="clear:both"></div>
-Authors: Frouws, T.D., Patterton, H.-G., Sewell, B.T.
+==See Also==
+*[[Histone 3D structures|Histone 3D structures]]
-Description: Model of Histone Octamer Tubular Crystals
+__TOC__
+</SX>
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan  7 09:31:26 2009''
+[[Category: Gallus gallus]]
+[[Category: Large Structures]]
+[[Category: Frouws TD]]