3fth: Difference between revisions
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New page: '''Unreleased structure''' The entry 3fth is ON HOLD Authors: Wiltzius, Jed J.W., Sawaya, Michael R., Eisenberg, D. Description: NFLVHSS segment from Islet Amyloid Polypeptide (IAPP or... |
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==NFLVHSS segment from Islet Amyloid Polypeptide (IAPP or Amylin)== | |||
<StructureSection load='3fth' size='340' side='right'caption='[[3fth]], [[Resolution|resolution]] 1.84Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3fth]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FTH FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
'' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fth FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fth OCA], [https://pdbe.org/3fth PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fth RCSB], [https://www.ebi.ac.uk/pdbsum/3fth PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fth ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/IAPP_HUMAN IAPP_HUMAN] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Eisenberg D]] | |||
[[Category: Sawaya MR]] | |||
[[Category: Wiltzius JJW]] | |||