1wl8: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
New page: left|200px<br /><applet load="1wl8" size="450" color="white" frame="true" align="right" spinBox="true" caption="1wl8, resolution 1.45Å" /> '''Crystal structure of...
 
OCA (talk | contribs)
No edit summary
 
(15 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1wl8.gif|left|200px]]<br /><applet load="1wl8" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1wl8, resolution 1.45&Aring;" />
'''Crystal structure of PH1346 protein from Pyrococcus horikoshii'''<br />


==About this Structure==
==Crystal structure of PH1346 protein from Pyrococcus horikoshii==
1WL8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii] with CL and ACY as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/GMP_synthase_(glutamine-hydrolyzing) GMP synthase (glutamine-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.5.2 6.3.5.2] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1WL8 OCA].  
<StructureSection load='1wl8' size='340' side='right'caption='[[1wl8]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
[[Category: GMP synthase (glutamine-hydrolyzing)]]
== Structural highlights ==
<table><tr><td colspan='2'>[[1wl8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WL8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WL8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=SNN:L-3-AMINOSUCCINIMIDE'>SNN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wl8 OCA], [https://pdbe.org/1wl8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wl8 RCSB], [https://www.ebi.ac.uk/pdbsum/1wl8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wl8 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wl8 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GUAAA_PYRHO GUAAA_PYRHO] Catalyzes the synthesis of GMP from XMP (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/1wl8_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wl8 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[GMP synthase|GMP synthase]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
[[Category: Single protein]]
[[Category: Kunishima N]]
[[Category: Kunishima, N.]]
[[Category: Lokanath NK]]
[[Category: Lokanath, N.K.]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: ACY]]
[[Category: CL]]
[[Category: gatases]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: transferase]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 05:30:11 2007''

Latest revision as of 04:59, 17 October 2024

Crystal structure of PH1346 protein from Pyrococcus horikoshii

1wl8, resolution 1.45Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA