3fwe: Difference between revisions

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New page: '''Unreleased structure''' The entry 3fwe is ON HOLD Authors: Sharma, H. Description: Crystal Structure of the Apo D138L CAP mutant ''Page seeded by [http://oca.weizmann.ac.il/oca OCA...
 
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'''Unreleased structure'''


The entry 3fwe is ON HOLD
==Crystal Structure of the Apo D138L CAP mutant==
<StructureSection load='3fwe' size='340' side='right'caption='[[3fwe]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3fwe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FWE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PRO:PROLINE'>PRO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwe OCA], [https://pdbe.org/3fwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fwe RCSB], [https://www.ebi.ac.uk/pdbsum/3fwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fwe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CRP_ECOLI CRP_ECOLI] This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons. The protein induces a severe bend in the DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP.<ref>PMID:2982847</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/3fwe_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fwe ConSurf].
<div style="clear:both"></div>


Authors: Sharma, H.
==See Also==
 
*[[Catabolite gene activator protein 3D structures|Catabolite gene activator protein 3D structures]]
Description: Crystal Structure of the Apo D138L CAP mutant
== References ==
 
<references/>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb  4 11:27:03 2009''
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Kong J]]
[[Category: Sharma H]]
[[Category: Steitz T]]
[[Category: Wang J]]
[[Category: Yu S]]
Retrieved from "https://proteopedia.org/3fwe"