Anderson Sandbox: Difference between revisions

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===A SMART Team Modeling Project from the CBM===
 
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==What is a SMART Team?==


====This is a Test Series of scenes for <scene name='Anderson_Sandbox/Orig/1'>Lac-Y Permease</scene>====
'''S'''- Students
'''M'''- Modeling
'''A'''
'''R'''- Research
'''T'''- Topic


To the right is an image representation of Lac-Y permese of E-coli. The Ligand is shown <scene name='Anderson_Sandbox/Ligand/3'>here</scene>, the Sidechains Participating in substrate binding are <scene name='Anderson_Sandbox/Sbu_binding_res/2'>here</scene>, and residues participating in proton translocation are here.
This is a program currently run by the Center for Biomolecular Modeling headed by Shannon Colton. We at the CBM do not do any of the research it's all the students that research and study what it is that their molecule does. These students are any where from Jr.High students to Seniors graduating from High School. Our job at the CBM is to put them in contact with a researcher that is interested in participating in the program and to help in making a physical model for the students to use when demonstrating what it is their molecule does.
[http://www.rpc.msoe.edu/cbm/smartteams/ www.rpc.msoe.edu/cbm/smartteams/]


====Function of Lactose Permease====
[[Image:(image info)|thumb|(Caption)]] 




Lactose Permease is a transmembrane  protein that facilitates the passage of lactose across the phospholipid bi-layer of the cell membrane.  The transport mechanism used is an active co-transport that uses the inwardly directed H+ electrochemical gradient as its driving force.  As a result, the lactose is accompanied from the periplasm to the cytoplasm of the cell by an H+ proton.<ref name="A. Green, et. al.">[http://www.jbc.org/cgi/content/full/275/30/23240]</ref>
'''''Why Should I join a SMART team?'''''


Lactose is a disaccharide carbohydrate found primarily in mammalian milk.  It is a disaccharide composed of the monosaccharides glucose and galactose.  When lactose is ingested, it is brought into cells in the digestive system by the protein Lactose Permease. Here it is broken down into its monosaccharide subunits by the enzyme lactase so it may be used in the process of cellular respiration.<ref name="G. Gidwani">[http://www.faqs.org/nutrition/Kwa-Men/Lactose-Intolerance.html]</ref>
*It's a great way to be introduced to modern research
*Looks good on a College application
*Good way to meet new people that are interested in the same things you are
*Most Importantly it's '''FUN!!'''


<applet load='1pv7' size='300' frame='true' align='right' caption='Image of Lac-y Permease' />
Highlighting the <scene name='Anderson_Sandbox/All_sulfurs/1'>Sulfur</scene> of the lactose permease protein.


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==Center for Biomolecular Modeling Physical Models==
and display another structure.
The MSOE Center for Biomolecular Modeling has created various physical models of Hemoglobin.  Posted is a video displaying one such model and a discussion of some of the properites of Hemoglobin it exhibits.  For more information about the CBM and the models we create, visit our site at [http://cbm.msoe.edu http://cbm.msoe.edu].
 
{{STRUCTURE_ | PDB=  |  SCENE=  }}
 
 
 
 
 
 




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==Different CBM Slogans==
==Different CBM Slogans==


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