3e8y: Difference between revisions

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{{Seed}}
[[Image:3e8y.jpg|left|200px]]


<!--
==Xray structure of scorpion toxin BmBKTx1==
The line below this paragraph, containing "STRUCTURE_3e8y", creates the "Structure Box" on the page.
<StructureSection load='3e8y' size='340' side='right'caption='[[3e8y]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3e8y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E8Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E8Y FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3e8y|  PDB=3e8y  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e8y OCA], [https://pdbe.org/3e8y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e8y RCSB], [https://www.ebi.ac.uk/pdbsum/3e8y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e8y ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KA191_MESMA KA191_MESMA] Selective inhibitor of high conductance calcium-activated potassium channels KCa1.1/KCNMA1. May be insect specific.<ref>PMID:15178692</ref> [PDB:3E8Y]
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Racemic protein crystallography, enabled by total chemical synthesis, has allowed us to determine the X-ray structure of native scorpion toxin BmBKTx1; direct methods were used for phase determination. This is the first example of a protein racemate that crystallized in space group I41/a.


===Xray structure of scorpion toxin BmBKTx1===
X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods.,Mandal K, Pentelute BL, Tereshko V, Kossiakoff AA, Kent SB J Am Chem Soc. 2009 Feb 4;131(4):1362-3. PMID:19133782<ref>PMID:19133782</ref>


From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 3e8y" style="background-color:#fffaf0;"></div>


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==See Also==
The line below this paragraph, {{ABSTRACT_PUBMED_19133782}}, adds the Publication Abstract to the page
*[[Potassium channel toxin 3D structures|Potassium channel toxin 3D structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 19133782 is the PubMed ID number.
== References ==
-->
<references/>
{{ABSTRACT_PUBMED_19133782}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
3E8Y is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E8Y OCA].
[[Category: Mesobuthus martensii]]
 
[[Category: Kent SBH]]
==Reference==
[[Category: Kossiakoff AA]]
<ref group="xtra">PMID:19133782</ref><references group="xtra"/>
[[Category: Mandal K]]
[[Category: Kent, S B.H.]]
[[Category: Pentelute BL]]
[[Category: Kossiakoff, A A.]]
[[Category: Tereshko V]]
[[Category: Mandal, K.]]
[[Category: Pentelute, B L.]]
[[Category: Tereshko, V.]]
[[Category: Direct method]]
[[Category: Ionic channel inhibitor]]
[[Category: Neurotoxin]]
[[Category: Potassium channel inhibitor]]
[[Category: Racemic protein]]
[[Category: Secreted]]
[[Category: Toxin]]
[[Category: Xray crystal stucture]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 11 12:41:42 2009''

Latest revision as of 01:45, 21 November 2024

Xray structure of scorpion toxin BmBKTx1

3e8y, resolution 1.10Å

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