1x37: Difference between revisions
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New page: left|200px<br /><applet load="1x37" size="450" color="white" frame="true" align="right" spinBox="true" caption="1x37" /> '''Structure of Bacillus subtilis Lon protease ... |
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== | ==Structure of Bacillus subtilis Lon protease SSD domain== | ||
<StructureSection load='1x37' size='340' side='right'caption='[[1x37]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1x37]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X37 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X37 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x37 OCA], [https://pdbe.org/1x37 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x37 RCSB], [https://www.ebi.ac.uk/pdbsum/1x37 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x37 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/LON1_BACSU LON1_BACSU] ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity). Has been implicated in preventing sigma(G) activity under non-sporulation conditions.[HAMAP-Rule:MF_01973] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x3/1x37_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x37 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Chen C]] | |||
[[Category: Chen | [[Category: Lee YL]] | ||
[[Category: Lee | [[Category: Lo SC]] | ||
[[Category: Lo | [[Category: Lou YC]] | ||
[[Category: Lou | [[Category: Wang I]] | ||
[[Category: Wang | [[Category: Wu SH]] | ||
[[Category: Wu | |||
Latest revision as of 13:56, 9 May 2024
Structure of Bacillus subtilis Lon protease SSD domain
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