2i4v: Difference between revisions

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{{Seed}}
[[Image:2i4v.png|left|200px]]


<!--
==HIV-1 protease I84V, L90M with TMC126==
The line below this paragraph, containing "STRUCTURE_2i4v", creates the "Structure Box" on the page.
<StructureSection load='2i4v' size='340' side='right'caption='[[2i4v]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2i4v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I4V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I4V FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DJR:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL+[(1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL]CARBAMATE'>DJR</scene></td></tr>
{{STRUCTURE_2i4v|  PDB=2i4v  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i4v OCA], [https://pdbe.org/2i4v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i4v RCSB], [https://www.ebi.ac.uk/pdbsum/2i4v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i4v ProSAT]</span></td></tr>
 
</table>
===HIV-1 protease I84V, L90M with TMC126===
== Function ==
 
[https://www.uniprot.org/uniprot/Q903J0_9HIV1 Q903J0_9HIV1]
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_16979654}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 16979654 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i4/2i4v_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_16979654}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2I4V is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I4V OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i4v ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:16979654</ref><references group="xtra"/>
</StructureSection>
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Hatada, M.]]
[[Category: Large Structures]]
[[Category: Hiv-1 protein inhibitor mutant]]
[[Category: Hatada M]]
[[Category: Hydrolase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:34:22 2009''

Latest revision as of 09:01, 21 February 2024

HIV-1 protease I84V, L90M with TMC126

2i4v, resolution 1.50Å

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