2qdq: Difference between revisions

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[[Image:2qdq.png|left|200px]]


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==Crystal structure of the talin dimerisation domain==
The line below this paragraph, containing "STRUCTURE_2qdq", creates the "Structure Box" on the page.
<StructureSection load='2qdq' size='340' side='right'caption='[[2qdq]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2qdq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QDQ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qdq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qdq OCA], [https://pdbe.org/2qdq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qdq RCSB], [https://www.ebi.ac.uk/pdbsum/2qdq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qdq ProSAT]</span></td></tr>
{{STRUCTURE_2qdq| PDB=2qdq |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/TLN1_MOUSE TLN1_MOUSE] Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qd/2qdq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qdq ConSurf].
<div style="clear:both"></div>


===Crystal structure of the talin dimerisation domain===
==See Also==
 
*[[Talin 3D structures|Talin 3D structures]]
 
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</StructureSection>
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[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 18157087 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18157087}}
 
==About this Structure==
2QDQ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDQ OCA].
 
==Reference==
<ref group="xtra">PMID:18157087</ref><references group="xtra"/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Barsukov, I L.]]
[[Category: Barsukov IL]]
[[Category: Bate, N.]]
[[Category: Bate N]]
[[Category: Critchley, D R.C.]]
[[Category: Critchley DRC]]
[[Category: Gingras, A R.]]
[[Category: Gingras AR]]
[[Category: Putz, N S.M.]]
[[Category: Putz NSM]]
[[Category: Abs3]]
[[Category: C-terminal actin binding site]]
[[Category: Dimerisation domain]]
[[Category: Latch domain]]
[[Category: Structural protein]]
[[Category: Talin]]
 
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