2bu1: Difference between revisions

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{{Seed}}
[[Image:2bu1.png|left|200px]]


<!--
==MS2-RNA HAIRPIN (5BRU -5) COMPLEX==
The line below this paragraph, containing "STRUCTURE_2bu1", creates the "Structure Box" on the page.
<StructureSection load='2bu1' size='340' side='right'caption='[[2bu1]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2bu1]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1e6t 1e6t]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BU1 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5BU:5-BROMO-URIDINE-5-MONOPHOSPHATE'>5BU</scene></td></tr>
{{STRUCTURE_2bu1| PDB=2bu1 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bu1 OCA], [https://pdbe.org/2bu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bu1 RCSB], [https://www.ebi.ac.uk/pdbsum/2bu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bu1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bu/2bu1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bu1 ConSurf].
<div style="clear:both"></div>


===MS2-RNA HAIRPIN (5BRU-5) COMPLEX===
==See Also==
 
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_11720290}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 11720290 is the PubMed ID number.
</StructureSection>
-->
[[Category: Escherichia phage MS2]]
{{ABSTRACT_PUBMED_11720290}}
[[Category: Large Structures]]
 
[[Category: Davis DR]]
==About this Structure==
[[Category: Fridborg K]]
2BU1 is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1e6t 1e6t]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BU1 OCA].
[[Category: Grahn E]]
 
[[Category: Helgstrand C]]
==Reference==
[[Category: Lago H]]
<ref group="xtra">PMID:11720290</ref><references group="xtra"/>
[[Category: Liljas L]]
[[Category: Enterobacterio phage ms2]]
[[Category: Moss T]]
[[Category: Davis, D.]]
[[Category: Stockley PG]]
[[Category: Fridborg, K.]]
[[Category: Stonehouse NJ]]
[[Category: Grahn, E.]]
[[Category: Sundaram M]]
[[Category: Helgstrand, C.]]
[[Category: Tars K]]
[[Category: Lago, H.]]
[[Category: Liljas, L.]]
[[Category: Moss, T.]]
[[Category: Stockley, P.]]
[[Category: Stonehouse, N.]]
[[Category: Sundaram, M.]]
[[Category: Tars, K.]]
[[Category: Capsid]]
[[Category: Capsid protein]]
[[Category: Hairpin]]
[[Category: Icosahedral virus]]
[[Category: Levivirus]]
[[Category: Rna-binding]]
[[Category: Structural protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:38:09 2009''

Latest revision as of 06:38, 1 May 2024

MS2-RNA HAIRPIN (5BRU -5) COMPLEX

2bu1, resolution 2.20Å

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