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New page: left|200px<br /><applet load="1xng" size="450" color="white" frame="true" align="right" spinBox="true" caption="1xng, resolution 1.7Å" /> '''Crystal Structure of ...
 
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[[Image:1xng.gif|left|200px]]<br /><applet load="1xng" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1xng, resolution 1.7&Aring;" />
'''Crystal Structure of NH3-dependent NAD+ synthetase from Helicobacter pylori'''<br />


==About this Structure==
==Crystal Structure of NH3-dependent NAD+ synthetase from Helicobacter pylori==
1XNG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori] with MG, DND and ATP as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/NAD(+)_synthase NAD(+) synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.1.5 6.3.1.5] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1XNG OCA].  
<StructureSection load='1xng' size='340' side='right'caption='[[1xng]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1xng]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XNG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=DND:NICOTINIC+ACID+ADENINE+DINUCLEOTIDE'>DND</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xng OCA], [https://pdbe.org/1xng PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xng RCSB], [https://www.ebi.ac.uk/pdbsum/1xng PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xng ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NADE_HELPY NADE_HELPY]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xn/1xng_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xng ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
Crystal structure of NH3-dependent NAD+ synthetase from Helicobacter pylori., Kang GB, Kim YS, Im YJ, Rho SH, Lee JH, Eom SH, Proteins. 2005 Mar 1;58(4):985-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15645437 15645437]
*[[NAD synthase|NAD synthase]]
__TOC__
</StructureSection>
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
[[Category: NAD(+) synthase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Eom SH]]
[[Category: Eom, S.H.]]
[[Category: Im YJ]]
[[Category: Im, Y.J.]]
[[Category: Kang GB]]
[[Category: Kang, G.B.]]
[[Category: Kim YS]]
[[Category: Kim, Y.S.]]
[[Category: Lee JH]]
[[Category: Lee, J.H.]]
[[Category: Rho SH]]
[[Category: Rho, S.H.]]
[[Category: ATP]]
[[Category: DND]]
[[Category: MG]]
[[Category: amidotransferase]]
[[Category: helicobacter pylori]]
[[Category: nh3-dependent nad+ synthetase]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 06:12:29 2007''

Latest revision as of 13:36, 13 March 2024

Crystal Structure of NH3-dependent NAD+ synthetase from Helicobacter pylori

1xng, resolution 1.70Å

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