1csr: Difference between revisions

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{{Seed}}
[[Image:1csr.png|left|200px]]


<!--
==Alpha-fluoro acid and alpha-fluoro amide analogs of acetyl-coa as inhibitors of of citrate synthase: effect of pka matching on binding affinity and hydrogen bond length==
The line below this paragraph, containing "STRUCTURE_1csr", creates the "Structure Box" on the page.
<StructureSection load='1csr' size='340' side='right'caption='[[1csr]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1csr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CSR FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAM:ALPHA-FLUORO-AMIDOCARBOXYMETHYLDETHIA+COENZYME+A+COMPLEX'>FAM</scene>, <scene name='pdbligand=OAA:OXALOACETATE+ION'>OAA</scene></td></tr>
{{STRUCTURE_1csr| PDB=1csr |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1csr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1csr OCA], [https://pdbe.org/1csr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1csr RCSB], [https://www.ebi.ac.uk/pdbsum/1csr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1csr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CISY_CHICK CISY_CHICK]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cs/1csr_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1csr ConSurf].
<div style="clear:both"></div>


===ALPHA-FLUORO ACID AND ALPHA-FLUORO AMIDE ANALOGS OF ACETYL-COA AS INHIBITORS OF OF CITRATE SYNTHASE: EFFECT OF PKA MATCHING ON BINDING AFFINITY AND HYDROGEN BOND LENGTH===
==See Also==
 
*[[Citrate Synthase 3D structures|Citrate Synthase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_7492547}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 7492547 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_7492547}}
 
==About this Structure==
1CSR is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CSR OCA].
 
==Reference==
<ref group="xtra">PMID:7492547</ref><references group="xtra"/>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Remington, S J.]]
[[Category: Large Structures]]
[[Category: Usher, K C.]]
[[Category: Remington SJ]]
[[Category: Oxo-acid-lyase]]
[[Category: Usher KC]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:20:43 2009''
Retrieved from "https://proteopedia.org/1csr"