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New page: left|200px<br /><applet load="1xry" size="450" color="white" frame="true" align="right" spinBox="true" caption="1xry, resolution 2.10Å" /> '''Crystal structure of...
 
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[[Image:1xry.gif|left|200px]]<br /><applet load="1xry" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1xry, resolution 2.10&Aring;" />
'''Crystal structure of Aeromonas proteolytica aminopeptidase in complex with bestatin'''<br />


==About this Structure==
==Crystal structure of Aeromonas proteolytica aminopeptidase in complex with bestatin==
1XRY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Vibrio_proteolyticus Vibrio proteolyticus] with ZN and BES as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Bacterial_leucyl_aminopeptidase Bacterial leucyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.10 3.4.11.10] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1XRY OCA].  
<StructureSection load='1xry' size='340' side='right'caption='[[1xry]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
[[Category: Bacterial leucyl aminopeptidase]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[1xry]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_proteolyticus Vibrio proteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XRY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XRY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BES:2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC+ACID'>BES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xry FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xry OCA], [https://pdbe.org/1xry PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xry RCSB], [https://www.ebi.ac.uk/pdbsum/1xry PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xry ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AMPX_VIBPR AMPX_VIBPR]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xr/1xry_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xry ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Vibrio proteolyticus]]
[[Category: Vibrio proteolyticus]]
[[Category: Blumberg, S.]]
[[Category: Blumberg S]]
[[Category: Gilboa, R.]]
[[Category: Gilboa R]]
[[Category: Rondeau, J.M.]]
[[Category: Rondeau J-M]]
[[Category: Shoham, G.]]
[[Category: Shoham G]]
[[Category: Tarnus, C.]]
[[Category: Tarnus C]]
[[Category: BES]]
[[Category: ZN]]
[[Category: aeromonas proteolytica aminopeptidase]]
[[Category: bestatin]]
[[Category: di-zinc metalloproteinases]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 06:18:22 2007''

Latest revision as of 07:38, 30 October 2024

Crystal structure of Aeromonas proteolytica aminopeptidase in complex with bestatin

1xry, resolution 2.10Å

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