3ddu: Difference between revisions

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{{Seed}}
[[Image:3ddu.png|left|200px]]


<!--
==Prolyl Oligopeptidase with GSK552==
The line below this paragraph, containing "STRUCTURE_3ddu", creates the "Structure Box" on the page.
<StructureSection load='3ddu' size='340' side='right'caption='[[3ddu]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3ddu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DDU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DDU FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.56&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=552:(6S)-1-CHLORO-3-[(4-FLUOROBENZYL)OXY]-6-(PYRROLIDIN-1-YLCARBONYL)PYRROLO[1,2-A]PYRAZIN-4(6H)-ONE'>552</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
{{STRUCTURE_3ddu| PDB=3ddu |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ddu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ddu OCA], [https://pdbe.org/3ddu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ddu RCSB], [https://www.ebi.ac.uk/pdbsum/3ddu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ddu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PPCE_HUMAN PPCE_HUMAN] Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dd/3ddu_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ddu ConSurf].
<div style="clear:both"></div>


===Prolyl Oligopeptidase with GSK552===
==See Also==
 
*[[Prolyl Endopeptidase|Prolyl Endopeptidase]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_18606544}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 18606544 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_18606544}}
 
==About this Structure==
3DDU is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DDU OCA].
 
==Reference==
<ref group="xtra">PMID:18606544</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Prolyl oligopeptidase]]
[[Category: Large Structures]]
[[Category: Haffner, C D.]]
[[Category: Haffner CD]]
[[Category: Madauss, K P.]]
[[Category: Madauss KP]]
[[Category: Miller, A B.]]
[[Category: Miller AB]]
[[Category: Reid, R A.]]
[[Category: Reid RA]]
[[Category: Endopeptidase]]
[[Category: Hydrolase]]
[[Category: Pop]]
[[Category: Prolyl oligopeptidase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:41:08 2009''

Latest revision as of 09:40, 21 February 2024

Prolyl Oligopeptidase with GSK552

3ddu, resolution 1.56Å

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