1s0p: Difference between revisions
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< | ==Structure of the N-Terminal Domain of the Adenylyl Cyclase-Associated Protein (CAP) from Dictyostelium discoideum.== | ||
<StructureSection load='1s0p' size='340' side='right'caption='[[1s0p]], [[Resolution|resolution]] 1.40Å' scene=''> | |||
You may | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1s0p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1pn1 1pn1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S0P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S0P FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s0p OCA], [https://pdbe.org/1s0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s0p RCSB], [https://www.ebi.ac.uk/pdbsum/1s0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s0p ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CAP_DICDI CAP_DICDI] May have a regulatory bifunctional role. Binds G-actin and PIP2. Involved in microfilament reorganization near the plasma membrane in a PIP2-regulated manner. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s0/1s0p_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s0p ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[3D Adenylyl cyclase 3D structures|3D Adenylyl cyclase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
< | |||
[[Category: Dictyostelium discoideum]] | [[Category: Dictyostelium discoideum]] | ||
[[Category: Bartunik | [[Category: Large Structures]] | ||
[[Category: Bourenkov | [[Category: Bartunik HD]] | ||
[[Category: Brandstetter | [[Category: Bourenkov GP]] | ||
[[Category: Holak | [[Category: Brandstetter H]] | ||
[[Category: Israel | [[Category: Holak TA]] | ||
[[Category: Janssen | [[Category: Israel L]] | ||
[[Category: Katchalova | [[Category: Janssen KP]] | ||
[[Category: Ksiazek | [[Category: Katchalova G]] | ||
[[Category: Noegel | [[Category: Ksiazek D]] | ||
[[Category: Schleicher | [[Category: Noegel AA]] | ||
[[Category: Schleicher M]] | |||
Latest revision as of 08:27, 14 February 2024
Structure of the N-Terminal Domain of the Adenylyl Cyclase-Associated Protein (CAP) from Dictyostelium discoideum.
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