2pn8: Difference between revisions

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~~{{Seed}}~~

~~[[Image:2pn8.png|left|200px]]~~

<!--

==Crystal structure of human peroxiredoxin 4 (thioredoxin peroxidase)==

~~The line below this paragraph, containing~~ "~~STRUCTURE_2pn8~~"~~, creates the~~ "~~Structure Box~~" ~~on the page~~.

~~You may change~~ the ~~PDB parameter (which sets~~ the ~~PDB file loaded into~~ the ~~applet)~~

== Structural highlights ==

~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~

<table><tr><td colspan='2'>[[2pn8]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PN8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PN8 FirstGlance]. <br>

~~or leave~~ the ~~SCENE parameter empty for the default display.~~

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr>

-->

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pn8 OCA], [https://pdbe.org/2pn8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pn8 RCSB], [https://www.ebi.ac.uk/pdbsum/2pn8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pn8 ProSAT]</span></td></tr>

~~{{STRUCTURE_2pn8~~| ~~PDB~~=2pn8 ~~| SCENE~~= }}

</table>

== Function ==

[https://www.uniprot.org/uniprot/PRDX4_HUMAN PRDX4_HUMAN] Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.<ref>PMID:9388242</ref>

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

Check<jmol>

<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pn/2pn8_consurf.spt"</scriptWhenChecked>

<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>

<text>to colour the structure by Evolutionary Conservation</text>

</jmolCheckbox>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pn8 ConSurf].

==~~=Crystal structure of human peroxiredoxin 4 (thioredoxin peroxidase)=~~==

==See Also==

*[[Peroxiredoxin 3D structures|Peroxiredoxin 3D structures]]

== References ==

==~~About this Structure~~==

~~2PN8 is a 10 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http:~~//~~oca.weizmann.ac.il/oca-bin/ocashort?id=2PN8 OCA].~~

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: ~~Peroxiredoxin~~]]

[[Category: Large Structures]]

[[Category: Arrowsmith~~, C A.~~]]

[[Category: Arrowsmith CA]]

[[Category: Cooper, C~~.]]~~

[[Category: Cooper C]]

~~[[Category: Delft, F von.~~]]

[[Category: Edwards A]]

[[Category: Edwards, A.]]

[[Category: Kavanagh KL]]

[[Category: Kavanagh~~, K L.~~]]

[[Category: Oppermann U]]

[[Category: Oppermann, U.]]

[[Category: Pilka ES]]

[[Category: Pilka~~, E S.]]~~

[[Category: Sundstrom M]]

~~[[Category: SGC, Structural Genomics Consortium.~~]]

[[Category: Weigelt J]]

[[Category: Sundstrom, M.]]

[[Category: Von Delft F]]

[[Category: Weigelt, J.]]

[[Category: ~~Oxidoreductase]~~]

~~[[Category: Peroxiredoxin~~]]

~~[[Category: Sgc]]~~

~~[[Category: Structural genomics consortium]]~~

~~[[Category: Thioredoxin]]~~

~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:26:42 2009''~~

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@@ Line 1: / Line 1: @@
-{{Seed}}
-[[Image:2pn8.png|left|200px]]
-<!--
+==Crystal structure of human peroxiredoxin 4 (thioredoxin peroxidase)==
-The line below this paragraph, containing "STRUCTURE_2pn8", creates the "Structure Box" on the page.
+<StructureSection load='2pn8' size='340' side='right'caption='[[2pn8]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2pn8]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PN8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PN8 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pn8 OCA], [https://pdbe.org/2pn8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pn8 RCSB], [https://www.ebi.ac.uk/pdbsum/2pn8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pn8 ProSAT]</span></td></tr>
-{{STRUCTURE_2pn8|  PDB=2pn8  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PRDX4_HUMAN PRDX4_HUMAN] Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.<ref>PMID:9388242</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pn/2pn8_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pn8 ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of human peroxiredoxin 4 (thioredoxin peroxidase)===
+==See Also==
+*[[Peroxiredoxin 3D structures|Peroxiredoxin 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-PN8 is a 10 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PN8 OCA].
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Peroxiredoxin]]
+[[Category: Large Structures]]
-[[Category: Arrowsmith, C A.]]
+[[Category: Arrowsmith CA]]
-[[Category: Cooper, C.]]
+[[Category: Cooper C]]
-[[Category: Delft, F von.]]
+[[Category: Edwards A]]
-[[Category: Edwards, A.]]
+[[Category: Kavanagh KL]]
-[[Category: Kavanagh, K L.]]
+[[Category: Oppermann U]]
-[[Category: Oppermann, U.]]
+[[Category: Pilka ES]]
-[[Category: Pilka, E S.]]
+[[Category: Sundstrom M]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Weigelt J]]
-[[Category: Sundstrom, M.]]
+[[Category: Von Delft F]]
-[[Category: Weigelt, J.]]
-[[Category: Oxidoreductase]]
-[[Category: Peroxiredoxin]]
-[[Category: Sgc]]
-[[Category: Structural genomics consortium]]
-[[Category: Thioredoxin]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:26:42 2009''