1k8k: Difference between revisions

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[[Image:1k8k.png|left|200px]]


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==Crystal Structure of Arp2/3 Complex==
The line below this paragraph, containing "STRUCTURE_1k8k", creates the "Structure Box" on the page.
<StructureSection load='1k8k' size='340' side='right'caption='[[1k8k]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1k8k]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K8K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K8K FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k8k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k8k OCA], [https://pdbe.org/1k8k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k8k RCSB], [https://www.ebi.ac.uk/pdbsum/1k8k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k8k ProSAT]</span></td></tr>
{{STRUCTURE_1k8k| PDB=1k8k |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/ARP3_BOVIN ARP3_BOVIN] Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k8/1k8k_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k8k ConSurf].
<div style="clear:both"></div>


===Crystal Structure of Arp2/3 Complex===
==See Also==
 
*[[Actin-related protein 3D structures|Actin-related protein 3D structures]]
 
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 11721045 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11721045}}
 
==About this Structure==
1K8K is a 7 chains structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K8K OCA].
 
==Reference==
<ref group="xtra">PMID:11721045</ref><references group="xtra"/>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Choe, S.]]
[[Category: Large Structures]]
[[Category: Higgs, H N.]]
[[Category: Choe S]]
[[Category: Kaiser, D A.]]
[[Category: Higgs HN]]
[[Category: Marchand, J B.]]
[[Category: Kaiser DA]]
[[Category: Pollard, T D.]]
[[Category: Marchand J-B]]
[[Category: Robinson, R C.]]
[[Category: Pollard TD]]
[[Category: Turbedsky, K.]]
[[Category: Robinson RC]]
[[Category: Beta-propeller]]
[[Category: Turbedsky K]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:53:42 2009''