2qkv: Difference between revisions

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{{Seed}}
[[Image:2qkv.png|left|200px]]


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==Crystal Structure of the C645S Mutant of the 5th PDZ Domain of InaD==
The line below this paragraph, containing "STRUCTURE_2qkv", creates the "Structure Box" on the page.
<StructureSection load='2qkv' size='340' side='right'caption='[[2qkv]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2qkv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QKV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QKV FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qkv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qkv OCA], [https://pdbe.org/2qkv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qkv RCSB], [https://www.ebi.ac.uk/pdbsum/2qkv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qkv ProSAT]</span></td></tr>
{{STRUCTURE_2qkv|  PDB=2qkv  |  SCENE=  }}
</table>
 
== Function ==
===Crystal Structure of the C645S Mutant of the 5th PDZ Domain of InaD===
[https://www.uniprot.org/uniprot/INAD_DROME INAD_DROME] Involved in the negative feedback regulation of the light-activated signaling cascade in photoreceptors through a calcium-mediated process. Interacts with tetrapeptide ligand located in C-terminal sequence of 3 key components of the visual cascade, tethering them and forming a macromolecular signaling phototransduction complex.<ref>PMID:7826638</ref> <ref>PMID:11342563</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qk/2qkv_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_17923089}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qkv ConSurf].
2QKV is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QKV OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:17923089</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Ranganathan, R.]]
[[Category: Large Structures]]
[[Category: Socolich, M.]]
[[Category: Ranganathan R]]
[[Category: Membrane]]
[[Category: Socolich M]]
[[Category: Pdz domain]]
[[Category: Peptide binding protein]]
[[Category: Scaffolding protein]]
[[Category: Sensory transduction]]
[[Category: Vision]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:06:29 2009''

Latest revision as of 09:16, 21 February 2024

Crystal Structure of the C645S Mutant of the 5th PDZ Domain of InaD

2qkv, resolution 1.55Å

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