1ys3: Difference between revisions

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New page: left|200px<br /><applet load="1ys3" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ys3, resolution 1.90Å" /> '''Crystal Structure of...
 
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[[Image:1ys3.gif|left|200px]]<br /><applet load="1ys3" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1ys3, resolution 1.90&Aring;" />
'''Crystal Structure of the ATP binding domain of PrrB from Mycobacterium Tuberculosis'''<br />


==About this Structure==
==Crystal Structure of the ATP binding domain of PrrB from Mycobacterium Tuberculosis==
1YS3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with TRS as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1YS3 OCA].  
<StructureSection load='1ys3' size='340' side='right'caption='[[1ys3]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1ys3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YS3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ys3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ys3 OCA], [https://pdbe.org/1ys3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ys3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ys3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ys3 ProSAT], [https://www.topsan.org/Proteins/XMTB/1ys3 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PRRB_MYCTU PRRB_MYCTU] Member of the two-component regulatory system PrrB/PrrA. Involved specifically in early intracellular multiplication of Mycobacterium. Probably phosphorylates PrrA.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ys/1ys3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ys3 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Single protein]]
[[Category: Nowak E]]
[[Category: Nowak, E.]]
[[Category: Panjikar S]]
[[Category: Panjikar, S.]]
[[Category: Tucker P]]
[[Category: Tucker, P.]]
[[Category: XMTB, Mycobacterium.Tuberculosis.Structural.Proteomics.Project.]]
[[Category: TRS]]
[[Category: atp-binding domain]]
[[Category: histidine kinase]]
[[Category: mycobacterium tuberculosis structural proteomics project]]
[[Category: structural genomics]]
[[Category: xmtb]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 07:00:50 2007''
Retrieved from "https://proteopedia.org/1ys3"