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New page: left|200px<br /><applet load="1yws" size="450" color="white" frame="true" align="right" spinBox="true" caption="1yws" /> '''Solution structure of YBL071w-A from Sacchar...
 
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[[Image:1yws.gif|left|200px]]<br /><applet load="1yws" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1yws" />
'''Solution structure of YBL071w-A from Saccharomyces cerevisiae.'''<br />


==About this Structure==
==Solution structure of YBL071w-A from Saccharomyces cerevisiae.==
1YWS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with ZN as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1YWS OCA].  
<StructureSection load='1yws' size='340' side='right'caption='[[1yws]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1yws]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YWS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yws OCA], [https://pdbe.org/1yws PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yws RCSB], [https://www.ebi.ac.uk/pdbsum/1yws PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yws ProSAT], [https://www.topsan.org/Proteins/NESGC/1yws TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPH3_YEAST DPH3_YEAST] Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. Required for conferring sensitivity to K.lactis zymocin.<ref>PMID:15485916</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yw/1yws_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yws ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Arrowsmith CH]]
[[Category: Arrowsmith, C.H.]]
[[Category: Guido V]]
[[Category: Guido, V.]]
[[Category: Lukin JA]]
[[Category: Lukin, J.A.]]
[[Category: NESG, Northeast.Structural.Genomics.Consortium.]]
[[Category: ZN]]
[[Category: nesg]]
[[Category: northeast structural genomics consortium]]
[[Category: ontario centre for structural proteomics]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomics]]
[[Category: zinc finger]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 07:06:24 2007''

Latest revision as of 08:07, 15 May 2024

Solution structure of YBL071w-A from Saccharomyces cerevisiae.

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