2v8s: Difference between revisions

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{{Seed}}
[[Image:2v8s.png|left|200px]]


<!--
==VTI1B HABC DOMAIN - EPSINR ENTH DOMAIN COMPLEX==
The line below this paragraph, containing "STRUCTURE_2v8s", creates the "Structure Box" on the page.
<StructureSection load='2v8s' size='340' side='right'caption='[[2v8s]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2v8s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V8S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V8S FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.22&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
{{STRUCTURE_2v8s|  PDB=2v8s  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v8s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v8s OCA], [https://pdbe.org/2v8s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v8s RCSB], [https://www.ebi.ac.uk/pdbsum/2v8s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v8s ProSAT]</span></td></tr>
 
</table>
===VTI1B HABC DOMAIN- EPSINR ENTH DOMAIN COMPLEX===
== Function ==
 
[https://www.uniprot.org/uniprot/EPN4_HUMAN EPN4_HUMAN] Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.<ref>PMID:12429846</ref> <ref>PMID:12538641</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2V8S is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V8S OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v8/2v8s_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v8s ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Collins, B M.]]
[[Category: Large Structures]]
[[Category: Mccoy, A J.]]
[[Category: Collins BM]]
[[Category: Miller, S E.]]
[[Category: McCoy AJ]]
[[Category: Owen, D J.]]
[[Category: Miller SE]]
[[Category: Adaptor]]
[[Category: Owen DJ]]
[[Category: Alternative splicing]]
[[Category: Cargo]]
[[Category: Clathrin]]
[[Category: Coiled coil]]
[[Category: Cytoplasm]]
[[Category: Cytoplasmic vesicle]]
[[Category: Endocytosis]]
[[Category: Lipid-binding]]
[[Category: Membrane]]
[[Category: Phosphorylation]]
[[Category: Protein transport]]
[[Category: Snare]]
[[Category: Transmembrane]]
[[Category: Transport]]
[[Category: Vesicle]]
[[Category: Vti1b-epsinr complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:30:28 2009''

Latest revision as of 07:07, 1 May 2024

VTI1B HABC DOMAIN - EPSINR ENTH DOMAIN COMPLEX

2v8s, resolution 2.22Å

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