1em9: Difference between revisions

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{{Seed}}
[[Image:1em9.png|left|200px]]


<!--
==ROUS SARCOMA VIRUS CAPSID PROTEIN: N-TERMINAL DOMAIN==
The line below this paragraph, containing "STRUCTURE_1em9", creates the "Structure Box" on the page.
<StructureSection load='1em9' size='340' side='right'caption='[[1em9]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1em9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rous_sarcoma_virus_-_Prague_C Rous sarcoma virus - Prague C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EM9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EM9 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_1em9| PDB=1em9 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1em9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1em9 OCA], [https://pdbe.org/1em9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1em9 RCSB], [https://www.ebi.ac.uk/pdbsum/1em9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1em9 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GAG_RSVP GAG_RSVP] Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity).  The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/em/1em9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1em9 ConSurf].
<div style="clear:both"></div>


===ROUS SARCOMA VIRUS CAPSID PROTEIN: N-TERMINAL DOMAIN===
==See Also==
 
*[[Gag polyprotein 3D structures|Gag polyprotein 3D structures]]
 
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
<!--
__TOC__
The line below this paragraph, {{ABSTRACT_PUBMED_10873863}}, adds the Publication Abstract to the page
</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 10873863 is the PubMed ID number.
[[Category: Large Structures]]
-->
[[Category: Rous sarcoma virus - Prague C]]
{{ABSTRACT_PUBMED_10873863}}
[[Category: Eisenmesser EZ]]
 
[[Category: Fitzon-Ostendorp T]]
==About this Structure==
[[Category: Kingston RL]]
1EM9 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EM9 OCA].
[[Category: Post CB]]
 
[[Category: Rossmann MG]]
==Reference==
[[Category: Schatz GW]]
<ref group="xtra">PMID:10873863</ref><references group="xtra"/>
[[Category: Vogt VM]]
[[Category: Rous sarcoma virus]]
[[Category: Eisenmesser, E Z.]]
[[Category: Fitzon-Ostendorp, T.]]
[[Category: Kingston, R L.]]
[[Category: Post, C B.]]
[[Category: Rossmann, M G.]]
[[Category: Schatz, G W.]]
[[Category: Vogt, V M.]]
[[Category: Virus/viral protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:49:39 2009''
Retrieved from "https://proteopedia.org/1em9"