2oz1: Difference between revisions

Latest revision as of 08:27, 13 August 2026

The SoxAX Complex of Rhodovulum Sulfidophilum

Structural highlights

2oz1 is a 8 chain structure with sequence from Rhodovulum sulfidophilum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.35Å
Ligands:	CSS, HEC
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SOXA_RHOSU C-type diheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the liberation of two electrons, which may be transferred from the SoxAX complex to another cytochrome c and which then may be used for reductive CO(2) fixation.^[1] ^[2] ^[3] ^[4]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Cheesman MR, Little PJ, Berks BC. Novel heme ligation in a c-type cytochrome involved in thiosulfate oxidation: EPR and MCD of SoxAX from Rhodovulum sulfidophilum. Biochemistry. 2001 Sep 4;40(35):10562-9. PMID:11523998
↑ Appia-Ayme C, Little PJ, Matsumoto Y, Leech AP, Berks BC. Cytochrome complex essential for photosynthetic oxidation of both thiosulfate and sulfide in Rhodovulum sulfidophilum. J Bacteriol. 2001 Oct;183(20):6107-18. PMID:11567011 doi:https://dx.doi.org/10.1128/JB.183.20.6107-6118.2001
↑ Bamford VA, Bruno S, Rasmussen T, Appia-Ayme C, Cheesman MR, Berks BC, Hemmings AM. Structural basis for the oxidation of thiosulfate by a sulfur cycle enzyme. EMBO J. 2002 Nov 1;21(21):5599-610. PMID:12411478
↑ Bradley JM, Marritt SJ, Kihlken MA, Haynes K, Hemmings AM, Berks BC, Cheesman MR, Butt JN. Redox and chemical activities of the hemes in the sulfur oxidation pathway enzyme SoxAX. J Biol Chem. 2012 Nov 23;287(48):40350-9. doi: 10.1074/jbc.M112.396192. Epub 2012, Oct 11. PMID:23060437 doi:https://dx.doi.org/10.1074/jbc.M112.396192

Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Cheesman MR, Little PJ, Berks BC. Novel heme ligation in a c-type cytochrome involved in thiosulfate oxidation: EPR and MCD of SoxAX from Rhodovulum sulfidophilum. Biochemistry. 2001 Sep 4;40(35):10562-9. PMID:11523998

[2] Appia-Ayme C, Little PJ, Matsumoto Y, Leech AP, Berks BC. Cytochrome complex essential for photosynthetic oxidation of both thiosulfate and sulfide in Rhodovulum sulfidophilum. J Bacteriol. 2001 Oct;183(20):6107-18. PMID:11567011 doi:https://dx.doi.org/10.1128/JB.183.20.6107-6118.2001

[3] Bamford VA, Bruno S, Rasmussen T, Appia-Ayme C, Cheesman MR, Berks BC, Hemmings AM. Structural basis for the oxidation of thiosulfate by a sulfur cycle enzyme. EMBO J. 2002 Nov 1;21(21):5599-610. PMID:12411478

[4] Bradley JM, Marritt SJ, Kihlken MA, Haynes K, Hemmings AM, Berks BC, Cheesman MR, Butt JN. Redox and chemical activities of the hemes in the sulfur oxidation pathway enzyme SoxAX. J Biol Chem. 2012 Nov 23;287(48):40350-9. doi: 10.1074/jbc.M112.396192. Epub 2012, Oct 11. PMID:23060437 doi:https://dx.doi.org/10.1074/jbc.M112.396192

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[2]

[3]

[4]

@@ Line 1: / Line 1: @@
-{{Seed}}
-[[Image:2oz1.png|left|200px]]
-<!--
+==The SoxAX Complex of Rhodovulum Sulfidophilum==
-The line below this paragraph, containing "STRUCTURE_2oz1", creates the "Structure Box" on the page.
+<StructureSection load='2oz1' size='340' side='right'caption='[[2oz1]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2oz1]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodovulum_sulfidophilum Rhodovulum sulfidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OZ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OZ1 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>
-{{STRUCTURE_2oz1|  PDB=2oz1  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oz1 OCA], [https://pdbe.org/2oz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oz1 RCSB], [https://www.ebi.ac.uk/pdbsum/2oz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oz1 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SOXA_RHOSU SOXA_RHOSU] C-type diheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the liberation of two electrons, which may be transferred from the SoxAX complex to another cytochrome c and which then may be used for reductive CO(2) fixation.<ref>PMID:11523998</ref> <ref>PMID:11567011</ref> <ref>PMID:12411478</ref> <ref>PMID:23060437</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oz/2oz1_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oz1 ConSurf].
+<div style="clear:both"></div>
-===The SoxAX Complex of Rhodovulum Sulfidophilum===
+==See Also==
+*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-OZ1 is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Rhodovulum_sulfidophilum Rhodovulum sulfidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OZ1 OCA].
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Rhodovulum sulfidophilum]]
-[[Category: Berks, B C.]]
+[[Category: Berks BC]]
-[[Category: Hemmings, A M.]]
+[[Category: Hemmings AM]]
-[[Category: Kihlken, M A.]]
+[[Category: Kihlken MA]]
-[[Category: Cysteine persulfide heme ligand]]
-[[Category: Cytochrome c]]
-[[Category: Electron transfer,bacterial sulfur cycle]]
-[[Category: Electron transport]]
-[[Category: Thiosulfate oxidation]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:49:42 2009''

2oz1: Difference between revisions

Latest revision as of 08:27, 13 August 2026

The SoxAX Complex of Rhodovulum Sulfidophilum

Structural highlights

Function

Evolutionary Conservation

See Also

References

Contents

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