1lqv: Difference between revisions

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{{Seed}}
[[Image:1lqv.png|left|200px]]


<!--
==Crystal structure of the Endothelial protein C receptor with phospholipid in the groove in complex with Gla domain of protein C.==
The line below this paragraph, containing "STRUCTURE_1lqv", creates the "Structure Box" on the page.
<StructureSection load='1lqv' size='340' side='right'caption='[[1lqv]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1lqv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LQV FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PTY:PHOSPHATIDYLETHANOLAMINE'>PTY</scene></td></tr>
{{STRUCTURE_1lqv|  PDB=1lqv  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lqv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lqv OCA], [https://pdbe.org/1lqv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lqv RCSB], [https://www.ebi.ac.uk/pdbsum/1lqv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lqv ProSAT]</span></td></tr>
 
</table>
===Crystal structure of the Endothelial protein C receptor with phospholipid in the groove in complex with Gla domain of protein C.===
== Function ==
 
[https://www.uniprot.org/uniprot/EPCR_HUMAN EPCR_HUMAN] Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_12034704}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 12034704 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lq/1lqv_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12034704}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1LQV is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQV OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lqv ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:12034704</ref><references group="xtra"/>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Dauter, Z.]]
[[Category: Large Structures]]
[[Category: Dongfeng, Q.]]
[[Category: Dauter Z]]
[[Category: Esmon, C T.]]
[[Category: Dongfeng Q]]
[[Category: Esmon, N L.]]
[[Category: Esmon CT]]
[[Category: Oganesyan, N.]]
[[Category: Esmon NL]]
[[Category: Oganesyan, V.]]
[[Category: Oganesyan N]]
[[Category: Terzyan, S.]]
[[Category: Oganesyan V]]
[[Category: Ca ion binding]]
[[Category: Terzyan S]]
[[Category: Phospholipid binding groove]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:52:18 2009''
Retrieved from "https://proteopedia.org/1lqv"