1z6l: Difference between revisions

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New page: left|200px<br /><applet load="1z6l" size="450" color="white" frame="true" align="right" spinBox="true" caption="1z6l, resolution 2.50Å" /> '''crystal structure of...
 
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[[Image:1z6l.gif|left|200px]]<br /><applet load="1z6l" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1z6l, resolution 2.50&Aring;" />
'''crystal structure of Fms1 in complex with its substrate'''<br />


==About this Structure==
==crystal structure of Fms1 in complex with its substrate==
1Z6L is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with FAD and DRE as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Polyamine_oxidase Polyamine oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.3.11 1.5.3.11] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1Z6L OCA].  
<StructureSection load='1z6l' size='340' side='right'caption='[[1z6l]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
[[Category: Polyamine oxidase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[1z6l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z6L FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DRE:N-(6-AMINOHEXYL)HEXANE-1,6-DIAMINE'>DRE</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z6l OCA], [https://pdbe.org/1z6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z6l RCSB], [https://www.ebi.ac.uk/pdbsum/1z6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z6l ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FMS1_YEAST FMS1_YEAST] Involved in the production of beta-alanine, a precursor of pantothenic acid. Multicopy suppressor of fenpropimorph resistance.<ref>PMID:12670477</ref> <ref>PMID:14617780</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z6/1z6l_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z6l ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Polyamine oxidase|Polyamine oxidase]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Hao Q]]
[[Category: Hao, Q.]]
[[Category: Huang Q]]
[[Category: Huang, Q.]]
[[Category: Liu Q]]
[[Category: Liu, Q.]]
[[Category: DRE]]
[[Category: FAD]]
[[Category: bis(hexamethylene)triamine]]
[[Category: crystal structure]]
[[Category: fms1]]
[[Category: polyamine oxidase]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 07:16:05 2007''