1z8f: Difference between revisions
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New page: left|200px<br /><applet load="1z8f" size="450" color="white" frame="true" align="right" spinBox="true" caption="1z8f, resolution 2.50Å" /> '''Guanylate Kinase Dou... |
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== | ==Guanylate Kinase Double Mutant A58C, T157C from Mycobacterium tuberculosis (Rv1389)== | ||
<StructureSection load='1z8f' size='340' side='right'caption='[[1z8f]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
[[Category: | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1z8f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z8F FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8f OCA], [https://pdbe.org/1z8f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z8f RCSB], [https://www.ebi.ac.uk/pdbsum/1z8f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z8f ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/KGUA_MYCTU KGUA_MYCTU] Essential for recycling GMP and indirectly, cGMP (By similarity).[HAMAP-Rule:MF_00328] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z8/1z8f_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z8f ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Chan S]] | |||
[[Category: Chan | [[Category: Choi B]] | ||
[[Category: Choi | [[Category: Perry LJ]] | ||
[[Category: Perry | [[Category: Sawaya MR]] | ||
[[Category: Sawaya | [[Category: Zocchi G]] | ||
[[Category: Zocchi | |||
Latest revision as of 08:57, 6 November 2024
Guanylate Kinase Double Mutant A58C, T157C from Mycobacterium tuberculosis (Rv1389)
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