1c48: Difference between revisions

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{{Seed}}
[[Image:1c48.png|left|200px]]


<!--
==MUTATED SHIGA-LIKE TOXIN B SUBUNIT (G62T)==
The line below this paragraph, containing "STRUCTURE_1c48", creates the "Structure Box" on the page.
<StructureSection load='1c48' size='340' side='right'caption='[[1c48]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1c48]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Phage_h30 Phage h30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C48 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C48 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c48 OCA], [https://pdbe.org/1c48 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c48 RCSB], [https://www.ebi.ac.uk/pdbsum/1c48 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c48 ProSAT]</span></td></tr>
{{STRUCTURE_1c48| PDB=1c48 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/STXB_BPH30 STXB_BPH30] The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c4/1c48_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c48 ConSurf].
<div style="clear:both"></div>


===MUTATED SHIGA-LIKE TOXIN B SUBUNIT (G62T)===
==See Also==
 
*[[Shiga toxin 3D structures|Shiga toxin 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1C48 is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Phage_h30 Phage h30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C48 OCA].
[[Category: Large Structures]]
[[Category: Phage h30]]
[[Category: Phage h30]]
[[Category: Bast, D.]]
[[Category: Bast D]]
[[Category: Brunton, J L.]]
[[Category: Brunton JL]]
[[Category: Ling, H.]]
[[Category: Ling H]]
[[Category: Read, R J.]]
[[Category: Read RJ]]
[[Category: Ob-fold]]
[[Category: Protein-carbohydrate recognition]]
[[Category: Receptor binding]]
[[Category: Toxin]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:29:00 2009''
Retrieved from "https://proteopedia.org/1c48"