1k0m: Difference between revisions

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{{Seed}}
[[Image:1k0m.png|left|200px]]


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==Crystal structure of a soluble monomeric form of CLIC1 at 1.4 angstroms==
The line below this paragraph, containing "STRUCTURE_1k0m", creates the "Structure Box" on the page.
<StructureSection load='1k0m' size='340' side='right'caption='[[1k0m]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1k0m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K0M FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k0m OCA], [https://pdbe.org/1k0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k0m RCSB], [https://www.ebi.ac.uk/pdbsum/1k0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k0m ProSAT]</span></td></tr>
{{STRUCTURE_1k0m| PDB=1k0m |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/CLIC1_HUMAN CLIC1_HUMAN] Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.<ref>PMID:9139710</ref> <ref>PMID:10834939</ref> <ref>PMID:11195932</ref> <ref>PMID:11940526</ref> <ref>PMID:11978800</ref> <ref>PMID:11551966</ref> <ref>PMID:14613939</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k0/1k0m_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k0m ConSurf].
<div style="clear:both"></div>


===Crystal structure of a soluble monomeric form of CLIC1 at 1.4 angstroms===
==See Also==
 
*[[Ion channels 3D structures|Ion channels 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_11551966}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11551966 is the PubMed ID number.
</StructureSection>
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{{ABSTRACT_PUBMED_11551966}}
 
==About this Structure==
1K0M is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K0M OCA].
 
==Reference==
<ref group="xtra">PMID:11551966</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bauskin, A R.]]
[[Category: Large Structures]]
[[Category: Breit, S N.]]
[[Category: Bauskin AR]]
[[Category: Campbell, T J.]]
[[Category: Breit SN]]
[[Category: Curmi, P M.G.]]
[[Category: Campbell TJ]]
[[Category: DeMaere, M Z.]]
[[Category: Curmi PMG]]
[[Category: Fairlie, W D.]]
[[Category: DeMaere MZ]]
[[Category: Harrop, S J.]]
[[Category: Fairlie WD]]
[[Category: Jankova, L.]]
[[Category: Harrop SJ]]
[[Category: Mazzanti, M.]]
[[Category: Jankova L]]
[[Category: Pankhurst, S.]]
[[Category: Mazzanti M]]
[[Category: Qiu, M R.]]
[[Category: Pankhurst S]]
[[Category: Reztsova, T.]]
[[Category: Qiu MR]]
[[Category: Tonini, R.]]
[[Category: Reztsova T]]
[[Category: Valenzuela, S M.]]
[[Category: Tonini R]]
[[Category: Warton, K.]]
[[Category: Valenzuela SM]]
[[Category: Wu, W M.]]
[[Category: Warton K]]
[[Category: Chloride ion channel]]
[[Category: Wu WM]]
[[Category: Glutathione-s-tranferase superfamily]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:35:56 2009''
Retrieved from "https://proteopedia.org/1k0m"