1iou: Difference between revisions

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{{Seed}}
[[Image:1iou.png|left|200px]]


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==SOLUTION STRUCTURE OF YKT6P (1-140)==
The line below this paragraph, containing "STRUCTURE_1iou", creates the "Structure Box" on the page.
<StructureSection load='1iou' size='340' side='right'caption='[[1iou]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1iou]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IOU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IOU FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iou FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iou OCA], [https://pdbe.org/1iou PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iou RCSB], [https://www.ebi.ac.uk/pdbsum/1iou PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iou ProSAT]</span></td></tr>
{{STRUCTURE_1iou|  PDB=1iou  |  SCENE=  }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/YKT6_YEAST YKT6_YEAST]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/io/1iou_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1iou ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Ykt6p is a nonsyntaxin SNARE implicated in multiple intracellular membrane trafficking steps. Here we present the structure of the NH2-terminal domain of Ykt6p (Ykt6pN, residues 1 to 140). The structure of Ykt6pN differed entirely from that of syntaxin and resembled the overall fold of the actin regulatory protein, profilin. Like some syntaxins, Ykt6p adopted a folded back conformation in which Ykt6pN bound to its COOH-terminal core domain. The NH2-terminal domain plays an important biological role in the function of Ykt6p, which in vitro studies revealed to include influencing the kinetics and proper assembly of SNARE complexes.


===SOLUTION STRUCTURE OF YKT6P (1-140)===
An autoinhibitory mechanism for nonsyntaxin SNARE proteins revealed by the structure of Ykt6p.,Tochio H, Tsui MM, Banfield DK, Zhang M Science. 2001 Jul 27;293(5530):698-702. PMID:11474112<ref>PMID:11474112</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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The line below this paragraph, {{ABSTRACT_PUBMED_11474112}}, adds the Publication Abstract to the page
<div class="pdbe-citations 1iou" style="background-color:#fffaf0;"></div>
(as it appears on PubMed at http://www.pubmed.gov), where 11474112 is the PubMed ID number.
== References ==
-->
<references/>
{{ABSTRACT_PUBMED_11474112}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
1IOU is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IOU OCA].
 
==Reference==
<ref group="xtra">PMID:11474112</ref><references group="xtra"/>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Banfield, D K.]]
[[Category: Banfield DK]]
[[Category: Tochio, H.]]
[[Category: Tochio H]]
[[Category: Tsui, M M.K.]]
[[Category: Tsui MMK]]
[[Category: Zhang, M.]]
[[Category: Zhang M]]
[[Category: Snare]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:47:16 2009''
Retrieved from "https://proteopedia.org/1iou"