1fxx: Difference between revisions

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{{Seed}}
[[Image:1fxx.png|left|200px]]


<!--
==THE STRUCTURE OF EXONUCLEASE I SUGGESTS HOW PROCESSIVITY IS ACHIEVED==
The line below this paragraph, containing "STRUCTURE_1fxx", creates the "Structure Box" on the page.
<StructureSection load='1fxx' size='340' side='right'caption='[[1fxx]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1fxx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FXX FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
{{STRUCTURE_1fxx| PDB=1fxx |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fxx OCA], [https://pdbe.org/1fxx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fxx RCSB], [https://www.ebi.ac.uk/pdbsum/1fxx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fxx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/EX1_ECOLI EX1_ECOLI] Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fx/1fxx_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fxx ConSurf].
<div style="clear:both"></div>


===THE STRUCTURE OF EXONUCLEASE I SUGGESTS HOW PROCESSIVITY IS ACHIEVED===
==See Also==
 
*[[Exonuclease|Exonuclease]]
 
*[[Exonuclease 3D structures|Exonuclease 3D structures]]
<!--
__TOC__
The line below this paragraph, {{ABSTRACT_PUBMED_11101894}}, adds the Publication Abstract to the page
</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 11101894 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_11101894}}
 
==About this Structure==
1FXX is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FXX OCA].
 
==Reference==
<ref group="xtra">PMID:11101894</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Exodeoxyribonuclease I]]
[[Category: Large Structures]]
[[Category: Breyer, W A.]]
[[Category: Breyer WA]]
[[Category: Matthews, B W.]]
[[Category: Matthews BW]]
[[Category: Alpha-beta domain]]
[[Category: Dnaq superfamily]]
[[Category: Sh3-like domain]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:48:27 2009''

Latest revision as of 07:20, 7 February 2024

THE STRUCTURE OF EXONUCLEASE I SUGGESTS HOW PROCESSIVITY IS ACHIEVED

1fxx, resolution 2.40Å

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