1uf5: Difference between revisions

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{{Seed}}
[[Image:1uf5.png|left|200px]]


<!--
==Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-methionine==
The line below this paragraph, containing "STRUCTURE_1uf5", creates the "Structure Box" on the page.
<StructureSection load='1uf5' size='340' side='right'caption='[[1uf5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1uf5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_sp. Agrobacterium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UF5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UF5 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CDT:4-METHYLSULFANYL-2-UREIDO-BUTYRIC+ACID'>CDT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
{{STRUCTURE_1uf5|  PDB=1uf5  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uf5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uf5 OCA], [https://pdbe.org/1uf5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uf5 RCSB], [https://www.ebi.ac.uk/pdbsum/1uf5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uf5 ProSAT]</span></td></tr>
 
</table>
===Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-methionine===
== Function ==
 
[https://www.uniprot.org/uniprot/DCAS_AGRSK DCAS_AGRSK] The enzyme catalyzes the hydrolysis of N-carbamoyl-D-amino acids to the corresponding which are useful intermediates in the preparation of beta-lactam antibiotics. Industrial production of beta-lactam antibiotics is now being developed using this enzyme.
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
1UF5 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Agrobacterium_sp. Agrobacterium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UF5 OCA].  
Check<jmol>
[[Category: Agrobacterium sp.]]
  <jmolCheckbox>
[[Category: N-carbamoyl-D-amino acid hydrolase]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uf/1uf5_consurf.spt"</scriptWhenChecked>
[[Category: Aoki, M.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Hashimoto, H.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Ikenaka, Y.]]
  </jmolCheckbox>
[[Category: Morikawa, H.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uf5 ConSurf].
[[Category: Nakai, T.]]
<div style="clear:both"></div>
[[Category: Sato, M.]]
__TOC__
[[Category: Shimizu, T.]]
</StructureSection>
[[Category: Takahashi, S.]]
[[Category: Agrobacterium sp]]
[[Category: Hydrolase]]
[[Category: Large Structures]]
 
[[Category: Aoki M]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:57:21 2009''
[[Category: Hashimoto H]]
[[Category: Ikenaka Y]]
[[Category: Morikawa H]]
[[Category: Nakai T]]
[[Category: Sato M]]
[[Category: Shimizu T]]
[[Category: Takahashi S]]
Retrieved from "https://proteopedia.org/1uf5"