2i6y: Difference between revisions

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{{Seed}}
[[Image:2i6y.png|left|200px]]


<!--
==Structure and Mechanism of Mycobacterium tuberculosis Salicylate Synthase, MbtI==
The line below this paragraph, containing "STRUCTURE_2i6y", creates the "Structure Box" on the page.
<StructureSection load='2i6y' size='340' side='right'caption='[[2i6y]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2i6y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I6Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I6Y FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i6y OCA], [https://pdbe.org/2i6y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i6y RCSB], [https://www.ebi.ac.uk/pdbsum/2i6y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i6y ProSAT], [https://www.topsan.org/Proteins/TBSGC/2i6y TOPSAN]</span></td></tr>
{{STRUCTURE_2i6y|  PDB=2i6y  |  SCENE=  }}
</table>
 
== Function ==
===Structure and Mechanism of Mycobacterium tuberculosis Salicylate Synthase, MbtI===
[https://www.uniprot.org/uniprot/MBTI_MYCTU MBTI_MYCTU] Mediates the production of salicylate from chorismate via an isochorismate intermediate. Presents both isochorismate synthase and isochorismate-pyruvate lyase activities. Salycilate is the starter unit in the production of the virulence-conferring salicylate-based siderophore mycobactin.<ref>PMID:16923875</ref>  
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
<!--
Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_17240979}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 17240979 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i6/2i6y_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_17240979}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i6y ConSurf].
2I6Y is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I6Y OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:17240979</ref><references group="xtra"/>
__TOC__
[[Category: Anthranilate synthase]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Kisker, C.]]
[[Category: Kisker C]]
[[Category: Subramaniapillai, K.]]
[[Category: Subramaniapillai K]]
[[Category: Tonge, P J.]]
[[Category: Tonge PJ]]
[[Category: Zhou, R.]]
[[Category: Zhou R]]
[[Category: Zwahlen, J.]]
[[Category: Zwahlen J]]
[[Category: Beta sheet]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 22:20:51 2009''

Latest revision as of 09:01, 21 February 2024

Structure and Mechanism of Mycobacterium tuberculosis Salicylate Synthase, MbtI

2i6y, resolution 2.50Å

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