1zyl: Difference between revisions

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New page: left|200px<br /><applet load="1zyl" size="450" color="white" frame="true" align="right" spinBox="true" caption="1zyl, resolution 2.80Å" /> '''Crystal Structure of...
 
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[[Image:1zyl.gif|left|200px]]<br /><applet load="1zyl" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1zyl, resolution 2.80&Aring;" />
'''Crystal Structure of Hypothetical Protein YihE from Escherichia coli'''<br />


==About this Structure==
==Crystal Structure of Hypothetical Protein YihE from Escherichia coli==
1ZYL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1ZYL OCA].  
<StructureSection load='1zyl' size='340' side='right'caption='[[1zyl]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1zyl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZYL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZYL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zyl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zyl OCA], [https://pdbe.org/1zyl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zyl RCSB], [https://www.ebi.ac.uk/pdbsum/1zyl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zyl ProSAT], [https://www.topsan.org/Proteins/BSGI/1zyl TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SRKA_ECOLI SRKA_ECOLI] A protein kinase that (auto)phosphorylates on Ser and Thr residues (PubMed:17302814). Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Protects cells from stress by antagonizing the MazE-MazF TA module, probably indirectly as it has not been seen to phosphorylate MazE, MazF or MazG (PubMed:23416055). Probably involved in the extracytoplasmic stress response (PubMed:9159398).[HAMAP-Rule:MF_01497]<ref>PMID:17302814</ref> <ref>PMID:23416055</ref> <ref>PMID:9159398</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zy/1zyl_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zyl ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: BSGI, Montreal-Kingston.Bacterial.Structural.Genomics.Initiative.]]
[[Category: Jia Z]]
[[Category: Jia, Z.]]
[[Category: Zheng J]]
[[Category: Zheng, J.]]
[[Category: bsgi]]
[[Category: hypothetical protein]]
[[Category: montreal-kingston bacterial structural genomics initiative]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: putative protein kinase ]]
[[Category: structural genomics]]
 
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