1f8n: Difference between revisions

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{{Seed}}
[[Image:1f8n.png|left|200px]]


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==LIPOXYGENASE-1 (SOYBEAN) AT 100K, NEW REFINEMENT==
The line below this paragraph, containing "STRUCTURE_1f8n", creates the "Structure Box" on the page.
<StructureSection load='1f8n' size='340' side='right'caption='[[1f8n]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1f8n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Glycine_max Glycine max]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F8N FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
{{STRUCTURE_1f8n|  PDB=1f8n  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f8n OCA], [https://pdbe.org/1f8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f8n RCSB], [https://www.ebi.ac.uk/pdbsum/1f8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f8n ProSAT]</span></td></tr>
 
</table>
===LIPOXYGENASE-1 (SOYBEAN) AT 100K, NEW REFINEMENT===
== Function ==
 
[https://www.uniprot.org/uniprot/LOX1_SOYBN LOX1_SOYBN] Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. With linoleate as substrate, L-1 shows a preference for carbon 13 as the site for hydroperoxidation (in contrast to L-2 and L-3, which utilize either carbon 9 or 13). At pH above 8.5, only (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate is produced, but as the pH decreases, the proportion of (9S)-hydroperoxide increases linearly until at pH 6.0 it represents about 25 % of the products.<ref>PMID:16157595</ref>  
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f8/1f8n_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_11412104}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1F8N is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Glycine_max Glycine max]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F8N OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f8n ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
<ref group="xtra">PMID:11412104</ref><references group="xtra"/>
<references/>
__TOC__
</StructureSection>
[[Category: Glycine max]]
[[Category: Glycine max]]
[[Category: Lipoxygenase]]
[[Category: Large Structures]]
[[Category: Holman, T.]]
[[Category: Holman T]]
[[Category: Minor, W.]]
[[Category: Minor W]]
[[Category: Tomchick, D R.]]
[[Category: Tomchick DR]]
[[Category: Dioxygenase]]
[[Category: Fatty acid]]
[[Category: Lipoxygenase]]
[[Category: Metalloprotein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:11:21 2009''