2oxo: Difference between revisions
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< | ==Crystallization and structure determination of the core-binding domain of bacteriophage lambda integrase== | ||
<StructureSection load='2oxo' size='340' side='right'caption='[[2oxo]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2oxo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteriophage_sp. Bacteriophage sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OXO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OXO FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oxo OCA], [https://pdbe.org/2oxo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oxo RCSB], [https://www.ebi.ac.uk/pdbsum/2oxo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oxo ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/VINT_LAMBD VINT_LAMBD] Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ox/2oxo_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oxo ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bacteriophage sp]] | |||
[[Category: Large Structures]] | |||
[[Category: Foster MP]] | |||
[[Category: | [[Category: Jain R]] | ||
[[Category: | [[Category: Kamadurai HB]] | ||
[[Category: | |||
[[Category: | |||
[[Category: | |||
Latest revision as of 09:06, 21 February 2024
Crystallization and structure determination of the core-binding domain of bacteriophage lambda integrase
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